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NCT Number: NCT07112118

Multimodal Identification of Depressive Symptoms in the Elderly

Screening with depression scales alone is subjective, and relying on single-modal data often leads to incomplete identification of symptoms that are easily missed or misdiagnosed. In this study, we first aim to use artificial intelligence to construct a depression symptom recognition model, concatenate multimodal features such as facial expression, audio, text, and postural behavior, and deeply fuse them to construct a multimodal model.

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Key information

Conditions

Depression Behavior Behavioral Symptoms

Age range

60 year–100 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Wuhan Mental Health Center

Wuhan, Hubei, 430012, China

Location contact

Xiuxiu Zhou, PhD

CONTACT

[email protected]

86+13545075638

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Elderly individuals aged 60 years or older.
  • Residents of the community (with residence time of more than 6 months).
  • Possessing certain reading, writing and comprehension skills, being able to communicate with researchers without obstacles, and being able to independently complete the measurement of various indicators or, although unable to independently fill out the questionnaire, being able to independently make evaluations of the questionnaire items.
  • Those who have given informed consent.

Exclusion criteria

  • Those who meet the diagnostic criteria for cognitive impairment (dementia) as stipulated in DSM-5, and/or who suffer from severe physical diseases (such as advanced cancer, cardiovascular and cerebrovascular diseases, etc.).
  • Those who are undergoing antidepressant treatment.
  • Elderly individuals who have had suicidal thoughts in any psychological assessment, should be referred to the psychological hotline platform in Wuhan.

Treatment and study plan

Data Collection

Other

Collect the facial expressions, audio, text and postural behavior data of the respondents using electronic devices.

Primary outcomes

  1. Use the PHQ-9 (Patient Health Questionnaire - 9 ) to assess whether the respondents have depressive symptoms. The scale score is one point for each item.

    Time frame: 2025.09.01-2026.09.01

    If the PHQ-9 score is 5 or higher, it is determined as a positive sign of depressive symptoms.

Study contacts

Contact information is provided by the study sponsor or research team.

Xiuxiu Zhou, PhD

CONTACT

[email protected]

86+13545075638

Sponsors and collaborators

Lead sponsor

Wuhan Mental Health Centre

Other

Registry information

Official study title

Multimodal Identification of Depressive Symptoms

Acronym: multimodal

Important dates

Study start
2025
Primary completion
2026
Study completion
2027
First posted
Aug 8, 2025
Registry last updated
Aug 11, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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