Multimodal Connectome Study of Brain Tumor-operated Patients

Patients included in the present study will first perform the pre-operative MRI (dMRI and fMRI) with a specific High Resolution Angular Diffusion (HARDI) sequence and a functional acquisition at rest. Then, the investigators will record their cortico-cortical evoked potentials elicited by direct electrostimulation during the surgery, just before the tumor removal, following our usual protocol. Finally, all data (clinical, diffusion, electrical and functional connectivity) will be processed and correlated to each other.

Inclusion criteria

• All patients with brain tumor for removal
• Age > 18 years
• Informed patient consent
• Membership of social security scheme

Exclusion criteria

• Contraindication to MRI
• Any subject with vascular stent implanted less than 6 weeks prior to the exam;
• Any subject carrying an intraocular or intracranial ferromagnetic foreign object close to nerve structures;
• Any subject carrying biomedical equipment such as a cardiac, neuronal or sensory pacemaker (cochlear implant) or a ventricular bypass valve without medical and paramedical supervision trained in the performance of MRI in these subjects;
• Presence of more than one brain tumor
• Refusal of patient participation
• Pregnant or nursing women. A urinary pregnancy test will be conducted for women of childbearing age. The results will be communicated to the patient by a doctor of her choice.
• Person staying in a health or social establishment
• Person in emergency situation
• Vulnerable patient: deprived of liberty, guardianship, curators, or safeguarding of justice