Hôpital Pitié-Salpêtrière
Paris, France
Location status: Recruiting
NCT Number: NCT06906042
Medical imaging is increasingly important for understanding diseases, detecting them early, and personalizing treatments. New imaging techniques, which can measure processes in the body without surgery, are opening the door to a more precise approach to medicine. Instead of relying on general probabilities, this technology allows us to analyze specific factors in a person's health, leading to better predictions and targeted treatments. One key challenge in medicine today is reducing "residual individual risk"-the remaining health risks that current treatments don't fully address. This involves understanding how factors like age, sex, genetics, and environment affect our health, particularly when it comes to conditions like heart and liver disease. By using imaging to distinguish between normal aging and disease, we can better assess individual health risks.
The current project will create a large collection of medical images linked with health data from a broad population across France. Using advanced, non-invasive techniques such as MRI and ultrasound, researchers will analyze the heart, blood vessels, and liver in detail, considering factors like gender and health risk profiles. This will help improve our understanding of these diseases, which are often silent and not well understood, providing direct benefits to the participants. Ultimately, the goal is to optimize imaging technologies for large-scale studies, which will help enhance early detection and prevention for everyone.
Interested in participating?
Request Info20 year and older
All sexes
Observational
Paris, France
Location status: Recruiting
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Echocardiography including: 12-lead digital ECG
Time frame: During 36 months of analysis (after 60 months of inclusion)
Ultrasound and MRI images analysis of qualitative and quantitative morphology, function, quantitative tissue characterization of the heart
Time frame: During 36 months of analysis (after 60 months of inclusion)
Ultrasound and MRI images analysis of qualitative and quantitative morphology, function, quantitative tissue characterization of the heart
Time frame: During 36 months of analysis (after 60 months of inclusion)
Ultrasound and MRI images analysis of quantitative steatosis, fibrosis
Time frame: During 36 months of analysis (after 60 months of inclusion)
Ultrasound and MRI images analysis of quantitative steatosis, fibrosis
Time frame: During 36 months of analysis (after 60 months of inclusion)
Ultrasound and MRI images analysis of volumes of subcutaneous, visceral and epicardial adipose tissues
Time frame: During 36 months of analysis (after 60 months of inclusion)
Ultrasound and MRI images analysis of volumes of subcutaneous, visceral and epicardial adipose tissues
Time frame: During 36 months of analysis (after 60 months of inclusion)
Analysis of the cardiac cavities in 2D, 3D and in deformation by echocardiography analysis
Time frame: During 36 months of analysis (after 60 months of inclusion)
Qualitative analysis of liver morphology and the nodularity of its boundaries, presence of ascites and portal derivation. Also presence of incidentaloma.
Time frame: During 36 months of analysis (after 60 months of inclusion)
Study of metabolic pathways and candidate biomarker suspected to be involved in aging
Time frame: During 36 months of analysis (after 60 months of inclusion)
Defining the minimum set of markers useful for creating a risk score
Contact information is provided by the study sponsor or research team.
Institut National de la Santé Et de la Recherche Médicale, France
Other Gov
Acronym: ICONIC
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT06299410
Healthy Volunteers
New Haven, Connecticut, United States
View Trial DetailsNCT07706686
Arbovirus Infections, Dengue
Bethesda, Maryland, United States
View Trial DetailsNCT02339012
Frail, Healthy Volunteers
Baltimore, Maryland, United States
View Trial DetailsNCT06552754
Healthy Volunteers, Virtual Reality
Ames, Iowa, United States
View Trial Details