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OpenTrials
Completed

NCT Number: NCT01196286

Multifamily Psychoeducation and Cognitive Remediation for Recent-Onset Psychosis

The goal of this study is to determine whether pairing multifamily group psychoeducation with cognitive remediation may facilitate improved outcomes among individuals with recent-onset psychosis.

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Key information

Age range

18 year–35 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Arizona

Tucson, Arizona, 85713, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

(Individual with Recent-Onset Psychosis):

  • Diagnosis of a non-substance induced psychotic disorder per DSM-IV-TR criteria determined using the Structured Clinical Interview for the DSM-IV.
  • Age between 18-35
  • Willing to participate in interventions at University of Arizona Medical Center, South Campus
  • Willing to complete research assessments
  • Duration of psychotic symptoms of less than 5 years determined using the Symptom Onset in Schizophrenia inventory
  • Able to provide informed consent
  • Fluent in English
  • Must have a family caregiver who is willing to participate in the study
  • Willing to allow videotaping of multifamily group therapy sessions.
  • No evidence of mental retardation as defined as never having qualified to receive services from the Arizona Department of Economic Security, Division of Developmental Disabilities.

Exclusion criteria

(Individual with Recent-Onset Psychosis):

  • Failure to meet inclusion criteria

Inclusion criteria

(Caregiving Relative of Individual with Recent-Onset Psychosis):

  • Must be someone that the individual with recent-onset psychosis identifies as providing support and care to the individual with recent-onset psychosis. Does not need to be a biological relative.
  • Must spend considerable time with the individual with recent-onset psychosis as defined at 10 hours or more of direct contact per week.
  • Willing to participate in participate in family intervention at University of Arizona Medical Center, South Campus for 2 years
  • Willing to complete research assessments
  • Able to provide informed consent
  • Fluent in English
  • Willing to allow videotaping of multifamily group sessions.

Exclusion criteria

(Caregiving Relative of Individual with Recent-Onset Psychosis):

  • Failure to meet inclusion criteria

Treatment and study plan

Multifamily Group Psychoeducation (MFG)

Behavioral

Participation in multifamily psychoeducation comprised of (i) three individual sessions with family and individual with psychosis, (ii) one psychoeducational workshop, and (iiI) twice monthly multifamily meetings to complete structured problem-solving activity

Cognitive Remediation (CR)

Behavioral

Computer exercises designed to improve cognitive functioning (3hr/wk).

Primary outcomes

  1. Psychotic Symptoms/Relapse Assessed Once Per Week

    Time frame: 9 months

Secondary outcomes

  1. Depression, Anxiety, Emotional Awareness, Cognitive Functioning, Problem-Solving Ability, Quality of Life, Social Functioning, Service Utilization

    Time frame: 9 months

Sponsors and collaborators

Lead sponsor

University of Arizona

Other

Collaborators

  • Institute for Mental Health Research

Registry information

Important dates

Study start
2010
Primary completion
2017
Study completion
2017
First posted
Sep 8, 2010
Registry last updated
May 21, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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