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NCT Number: NCT07183982

Multidisciplinary Rehabilitation Program for Treatment-Resistant Psychotic Forensic Patients: A Comparative Study

This study employs a quasi-experimental design to evaluate the effectiveness of a 6-month multidisciplinary rehabilitation program integrating psychodynamic group therapy, art therapy, music therapy, and cognitive stimulation compared to standard rehabilitation (physiotherapy and occupational therapy). It will be done between a group of a total of 20 patients are divided into an intervention group and a control group from the forensic psychiatric department in Al Masarra Hospital.

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Key information

Age range

18 year and older

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Al Massara Hospital

Muscat, Muḩāfaz̧at Masqaţ, Oman

About this study

Forensic psychiatric patients with treatment-resistant psychotic symptoms often experience persistent cognitive, functional, and social deficits, posing significant challenges to rehabilitation. Traditional approaches may not adequately address these complex needs, highlighting the importance of innovative, multidisciplinary interventions. This study employs a quasi-experimental design to evaluate the effectiveness of a 6-month multidisciplinary rehabilitation program integrating psychodynamic group therapy, art therapy, music therapy, and cognitive stimulation compared to standard rehabilitation (physiotherapy and occupational therapy). A total of 20 patients are divided into an intervention group (n=10) and a control group (n=10) using convenience sampling from the forensic psychiatric department in Al Masarra Hospital. Data is collected using the Positive and Negative Syndrome Scale (PANSS) to assess psychotic symptoms and the Montreal Cognitive Assessment (MoCA) to evaluate cognitive function, administered at baseline and post-intervention. Data is analyzed using descriptive statistics (median, interquartile range) and non-parametric tests, including the Wilcoxon Signed-Rank Test for within-group comparisons and the Mann-Whitney U Test for between-group comparisons. Effect sizes are calculated using Cliff's Delta to assess the practical significance of the findings. The null hypothesis states that there will be no significant difference in PANSS and MoCA scores between the intervention and control groups post-intervention. If the null hypothesis is rejected, the findings will provide evidence for integrating creative and psychotherapeutic interventions into forensic psychiatric rehabilitation, offering a scalable model for similar settings.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Diagnosis of chronic psychotic disorder (e.g., schizophrenia or schizoaffective disorder) confirmed by psychiatric assessment and medical records.
  • Presence of residual psychotic symptoms (positive symptoms such as hallucinations, delusions; and/or negative symptoms such as blunted affect, social withdrawal) despite ongoing psychotropic treatment.
  • Medically stable and deemed suitable for participation by the treating psychiatrist or healthcare team.
  • Patients who provide informed consent to participate in the rehabilitation program and research study.

Exclusion criteria

  • Acute medical or psychiatric conditions requiring immediate intervention.
  • Developmental or intellectual disabilities that significantly impair participation in the rehabilitation program or assessments.
  • Current substance dependence that would interfere with participation.
  • Significant risk of harm to self or others, based on clinical assessment or history of violence/aggression.
  • Contraindications to specific rehabilitation program components (e.g., physical exercise, group activities) as determined by medical evaluation.
  • Inability to comprehend study requirements or provide informed consent due to language barriers, cognitive impairment, or other factors.

Treatment and study plan

MoCA: Montreal Cognitive Assessment (MoCA) and Positive and Negative Syndrome Scale (PANSS)

Diagnostic Test

MoCA: A 30-point screening tool assessing attention, memory, language, visuospatial and executive functions; quick and sensitive to mild cognitive deficits.

PANSS: A 30-item scale rating positive, negative, and general psychopathology symptoms in psychotic disorders; widely used to track severity and change.

Rehabilitation program in the form of : psychodynamic group therapy, music and art therapy , cognitive stimulation techniques

Behavioral

Participants received a structured 6-month program designed to address persistent psychotic symptoms and associated deficits. The intervention included:

Art Therapy: Weekly sessions promoting self-expression, emotional regulation, and enhancement of social interaction.

Cognitive Stimulation: Structured group exercises aimed at improving attention, memory, executive functions, and problem-solving.

The program was delivered by a multidisciplinary team in a group of 10 patients, ensuring active participation, individualized support, and integration of therapeutic modalities.

Primary outcomes

  1. Change in Psychotic Symptoms Measured by the Positive and Negative Syndrome Scale (PANSS)

    Time frame: Baseline (pre-intervention) and 6 months (post-intervention).

    Psychotic symptom severity will be assessed using the Positive and Negative Syndrome Scale (PANSS). Scores range from 30 to 210, with higher scores indicating greater severity. The unit of measure is score change from baseline to post-intervention.

Secondary outcomes

  1. Change in Cognitive Function Measured by the Montreal Cognitive Assessment (MoCA) scale

    Time frame: Baseline (pre-intervention) and 6 months (post intervention).

    Cognitive function will be assessed using the Montreal Cognitive Assessment (MoCA) scale. Scores range from 0 to 30, with higher scores indicating better cognitive performance. The unit of measure is score change from baseline to post-intervention.

Sponsors and collaborators

Lead sponsor

Oman Ministry of Health

Other Gov

Registry information

Official study title

Effectiveness of a Multidisciplinary Rehabilitation Program for Treatment-Resistant Psychotic Patients in a Forensic Psychiatric Setting: A Comparative Study

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Sep 19, 2025
Registry last updated
Sep 19, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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