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Recruiting

NCT Number: NCT05880797

Multidimensional and Multimodal Profiling of Oropharyngeal Carcinoma

The purpose of this study is to better understand the natural history of oropharyngeal carcinoma (OPC), with or without an association with the human papilloma virus (HPV). For this study, the investigators plan to collect blood from OPC patients prior to treatment and at six subsequent time points.

Recruiting

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Key information

Conditions

Oropharyngeal Carcinoma Head and Neck Neoplasms Human Papilloma Virus Neoplasms Neoplasms by Site Oropharyngeal Neoplasms Otorhinolaryngologic Diseases Otorhinolaryngologic Neoplasms Pharyngeal Diseases Pharyngeal Neoplasms Stomatognathic Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Stanford University

Palo Alto, California, 94305, United States

Location status: Recruiting

Location contact

Nikita Bedi

CONTACT

[email protected]

650-723-5957

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients diagnosed with oropharyngeal carcinoma or patients with cancer of the unknown primary that is HPV associated, or possibly deemed to be originating from the oropharynx.

Exclusion criteria

  • Not willing to sign consent

Treatment and study plan

Primary outcomes

  1. Sample collection

    Time frame: prior to start of treatment

    30-50cc of blood

  2. Sample collection

    Time frame: up to 36 months post-op

    30-50cc of blood

Secondary outcomes

  1. tumor sample

    Time frame: Day 1

    tumor sample (FFPE) or fresh tissue post-excision or surgery, this will only be collected, if and when feasible, after the tumor has been removed post procedure.

Study contacts

Contact information is provided by the study sponsor or research team.

Nikita Bedi

CONTACT

[email protected]

(650) 723-5957

Sponsors and collaborators

Lead sponsor

Stanford University

Other

Registry information

Important dates

Study start
2023
Primary completion
2026
Study completion
2026
First posted
May 30, 2023
Registry last updated
Apr 13, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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