Multicenter Validation of the Salivary miRNA Signature of Endometriosis

Inclusion criteria

• Patient aged between 18 and 43 years,
• Patient having dated and signed the consent form,
• Patient affiliated to the French health system,
• Patient with pelvic MRI and/or pelvic ultrasound,
• Patient from one of the 3 study populations:

• Patient with a formal endometriosis diagnosed by clinical examination and imaging AND an indication for specialised endometriosis follow-up or medically assisted procreation (MAP) or surgery validated by RCP (in routine care);
• Patient with suspected endometriosis for whom the diagnosis is the source of a discrepancy between clinical and radiological data AND a surgical indication validated by RCP (in routine care);
• Patient with a gynaecological indication for surgery of the small pelvis by laparoscopy or laparoscopy validated in RCP (in routine care) AND symptoms suggestive of endometriosis (dysmenorrhoea, ....)(1).

Exclusion criteria

• Patient with recurrence of deep endometriosis (excluding endometrioma),
• Patient with endometriosis of the torus and/or utero-sacral ligaments without indication for surgery,
• Patient with parietal endometriosis alone without indication for surgery,
• Patient with adenomyosis alone on imaging without indication for surgery,
• Patient with gynaecological infection requiring surgical management,
• Pregnant patient,
• Patient infected with the human immunodeficiency virus (HIV),
• Patient with significant difficulties in reading or writing the French language,
• Patient with a personal history of cancer,
• Patient unable to comply with study and/or follow-up procedures,
• Patient who has objected to the collection of her data.
• Patient participating in another clinical research study.