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NCT Number: NCT07374861

Multicenter Study on the Evaluation of Adherence, Persistence and Efficacy of Treatment With Bempedoic Acid in Italy

Evaluation of adherence, persistence, and efficacy of treatment with Bempedoic acid in a real-life Italian population.

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Key information

Conditions

Hypercholesterolemia Dyslipidemias Hyperlipidemias Lipid Metabolism Disorders Metabolic Diseases Nutritional and Metabolic Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Federico II University of Naples, Department of Advanced Biomedical Sciences

Naples, Napoli, 80131, Italy

Location status: Recruiting

Location contact

Pasquale Perrone Filardi

CONTACT

[email protected]

+39081/7462224

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients under Bempedoic acid treatment

Exclusion criteria

  • Age < 18 years o > 80 years
  • Patients who refuse to participate and to sign informed consent

Treatment and study plan

Bempedoic acid

Drug

film-coated tablets

Primary outcomes

  1. Description of adherence to treatment with Bempedoic acid in a real-life Italian population

    Time frame: 6-12-24-36 months

    Adherence will be assessed in terms of Medical Possession Ratio (MPR), which is defined as the ratio between the treatment units dispensed during the treatment period and the duration of the treatment period itself.

  2. Description of efficacy of treatment with Bempedoic acid in a real-life Italian population

    Time frame: 6-12-24-36 months

    Efficacy of treatment will be evaluated as a change in the LDL (deltaLDL) value from the start of treatment (percentage and absolute value).

  3. Description of persistence to treatment with Bempedoic acid in a real-life Italian population

    Time frame: 6-12-24-36 months

    Persistence will be assessed in terms of therapeutic continuity from the start of treatment to enrollment.

Secondary outcomes

  1. Description of safety of treatment with Bempedoic acid in a real-life Italian population

    Time frame: 6-12-24-36 months

    Safety will be evaluated in terms of adverse reactions or intolerance to the drug.

Study contacts

Contact information is provided by the study sponsor or research team.

Pasquale Perrone Filardi

CONTACT

[email protected]

+39081/7462224

Sponsors and collaborators

Lead sponsor

Federico II University

Other

Registry information

Acronym: BEMPENET

Important dates

Study start
2025
Primary completion
2026
Study completion
2028
First posted
Jan 29, 2026
Registry last updated
Jan 29, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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