Recruiting

NCT Number: NCT06711861

Multicenter Retrospective Study on Streptobacillus Moniliformis Infections in France

French data on Streptobacillus moniliformis infections (zoonosis transmitted by rat bites) are rare and there are no case series in the literature to date. This is a pathology presenting atypical clinical manifestations for a bacterial infection and which therefore remains underdiagnosed. Streptobacillus moniliformis infections can be fatal without appropriate antibiotic treatment. This study could improve diagnosis, develop early treatment strategies and contribute to the overall understanding of zoonotic diseases

Recruiting

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Key information

Conditions

Streptobacillus Moniliformis Infections Animal Diseases Bacterial Infections Bacterial Infections and Mycoses Gram-Negative Bacterial Infections Infections Rat-Bite Fever Zoonoses

Age range

1 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Service des Maladies Infectieuses et Tropicales - CHU de Strasbourg - France

Strasbourg, 67091, France

Location status: Recruiting

Location contact

Amandine ROBERT, MD

PRINCIPAL_INVESTIGATOR

François DANION, MD

CONTACT

[email protected]

33 3 69 55 15 88

François DANION, MD

PRINCIPAL_INVESTIGATOR

Frédéric SCHRAMM, MD

SUB_INVESTIGATOR

GUILLOUZOUIC GUILLOUZOUIC, PharmD

PRINCIPAL_INVESTIGATOR

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Minor patient aged 1 to 17 years
Adult patient ≥18 years
Proven Streptobacillus moniliformis infection between 01/01/2007 and 31/12/2023
Subject not objecting, after being informed, to the reuse of their data for the purposes of this research
Holders of parental authority not objecting, after being informed, to the reuse of their data for the purposes of this research their child for the purposes of this research

Exclusion criteria

Subject and/or holder of parental authority having expressed opposition to participating in the study

Treatment and study plan

Primary outcomes

Retrospective study of the effectiveness of antibiotic therapy initiated for the treatment of Streptobacillus moniliformis infection.

Time frame: Negative blood culture 15 days after the start of antibiotic therapy.

Clinical cure 15 days after the start of antibiotic therapy. This cure is based on a negative blood culture (absence of germs) performed 15 days after the start of treatment.

Study contacts

Contact information is provided by the study sponsor or research team.

François DANION, MD

CONTACT

[email protected]

33 3 69 55 15 88

Sponsors and collaborators

Lead sponsor

University Hospital, Strasbourg, France

Other

Registry information

Acronym: Streptobacil

Important dates

Study start: 2024
Primary completion: 2025
Study completion: 2025
First posted: Dec 2, 2024
Registry last updated: Dec 2, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Recruiting