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Completed

NCT Number: NCT05933902

Multicenter Retrospective Observational Study of Acute Myocarditis in Korea

In this study, the investigators analyze the clinical characteristics and prognosis of patients with acute myocarditis in South Korea

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Key information

Conditions

Myocarditis Acute

Sex eligibility

All sexes

Study type

Observational

Primary location

Samsung Medical Center

Seoul, 06351, South Korea

About this study

Acute myocarditis refers to a condition in which inflammatory cells infiltrate the heart muscle due to various causes. Until now, there is no clear treatment method for myocarditis itself, and when myocardial function deteriorates or arrhythmia occurs due to myocarditis, it is common to wait for natural recovery while performing general supportive treatment for heart failure.

Through this study, the investigators analyze the factors contributing to the long-term prognosis, myocardial recovery rate, and clinical course of myocarditis. And, the investigators plan to establish an appropriate treatment strategy necessary to increase the survival rate of patients with myocarditis.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Typical myocarditis symptom and sign, such as fever, chest pain, chest discomfort or shortness of breath, accompanied by elevated myocardial enzymes
  • The above condition is satisfied and additional information is obtained through imaging such as cardiac MRI or cardiac biopsy

Exclusion criteria

● Coronary artery disease

Treatment and study plan

Primary outcomes

  1. Rate of In hospital mortality

    Time frame: through study completion, an average of 1 year

    In hospital death by any cause

Secondary outcomes

  1. Rate of all-cause mortality

    Time frame: through study completion, an average of 1 year

    Death by any cause during follow-up

  2. Requirement of cardiac replacement therapy

    Time frame: through study completion, an average of 1 year

    Left ventricular assist device insertion or heart transplantation during follow-up

  3. Rates of Re-hospitalization due to any cause

    Time frame: through study completion, an average of 1 year

    Re-hospitalization due to any cause during follow-up

Sponsors and collaborators

Lead sponsor

Samsung Medical Center

Other

Collaborators

  • Asan Medical Center
  • Chonnam National University Hospital
  • Keimyung University Dongsan Medical Center
  • Korea University Anam Hospital
  • Sejong General Hospital

Registry information

Official study title

Multicenter Retrospective Observational Study to Investigate the Characteristics and Prognosis of Patients With Acute Myocarditis in Korea

Important dates

Study start
2022
Primary completion
2023
Study completion
2023
First posted
Jul 6, 2023
Registry last updated
Jul 6, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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