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NCT Number: NCT05744973

Multi-level Predictors of Structural Racism and Discrimination and Associations With Health and Well-being Across the Life Course in Diverse Families

Minoritized populations face mutually reinforcing levels of structural disadvantage that contribute to poor health. Despite recognition that social and economic stratification, environmental conditions, and policy are critical determinants of health disparities, there has been limited effort in expanding interventions beyond the individual level to disrupt systemic causes of health. This is in part due to the challenges of describing how racism and discrimination have become systematized over time and across place.68 Studies that do examine SRD and health and well-being, focus on one level of SRD at a time, rather than examining multiple levels simultaneously. Also, the measurement of SRD at all levels has not been very detailed and more research is needed on the nuances of these experiences (e.g., frequency, timeframe, intensity). Finally, there is a need for more prospective longitudinal studies, as most research to date has been cross-sectional. In addition to comprehensively examining the four SRD levels, the current study will examine these multi- level predictors of SRD simultaneously, longitudinally, and across two sites to identify targets for multi-level interventions that will be more likely to be effective and sustainable.

Recruiting

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Key information

Age range

8 year–18 year

Sex eligibility

All sexes

Study type

Observational

Primary location

University of Georgia, Athens, Georgia, United States

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Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • willingness to provide informed consent (parent/guardian), parental consent (parent/guardian) and assent (minor participants) and the ability for participants to comply with study requirements
  • They are the child's primary caregiver, i.e., they are the adult who spends the largest proportion of time caring for the child (e.g., cleaning, feeding, etc.) or they spent an exactly equal proportion to another caregiver (e.g., parents each with 50% of childcare responsibilities).
  • They reside in Athens-Clarke County or surrounding counties (i.e., Barrow, Jackson, Madison, Oglethorpe, and Oconee) served by the Piedmont Healthcare Coalition region
  • Have access to a smartphone or other internet-connected device (e.g., iPad; home computer; laptop)
  • Are able to read either English or Spanish

UMN site:

  • participation in the original Family Matters Ecological Momentary Assessment sub-study
  • did not withdraw from the Family Matters study
  • ability to participate in an in-person visit (e.g., within driving distance to make an in-person visit)
  • The original Family Matters study enrolled vulnerable populations including children, pregnant women, disadvantaged persons, and non-English speakers.

UGA site:

  • Child has a racial/ethnic identity reported by the parent as Black, Hispanic, or White Reside in Athens-Clarke County or surrounding counties (i.e., Barrow, Jackson, Madison, Oglethorpe, and Oconee) served by the Piedmont Healthcare Coalition region
  • Have access to a smartphone or other internet-connected device (e.g., iPad; home computer; laptop)
  • Are able to read either English or Spanish
  • Aged 8 to 18 years old

Exclusion criteria

  • Medically necessary dietary restrictions (e.g., feeding tubes)
  • BMI < 5%ile
  • A diagnosis of a serious and persistent mental illness
  • The child's parent/caregiver believes that the child is not developmentally able to participate in study components (e.g., severe autism)
  • The family already has one parent or one child enrolled in the study
  • There are no more availabilities in the family's census tract (limited to 10 households per tract). UGA also is interested in recruiting families from a range of census tracts in the Athens, GA area. If UGA finds that many families are coming from a few census tracts, they may restrict enrollment of new participants who are from those already-represented census tracts.

Treatment and study plan

No intervention

Other

This is an observational study

Primary outcomes

  1. changes in cardiometabolic risk score

    Time frame: baseline to 18 months

    comprised of 5 cardiometabolic indicators of lower health - overweight status, triglyceride to HDL ratio, c-reactive protein , stage 1 or 2 hypertension, and elevated HbA1c &gt;= 5.7across two time points 18 months apart collected in children and adults

Secondary outcomes

  1. Change in Mental health (parent and child)

    Time frame: baseline to 18 months

    Change in depression scores using Kessler 6

  2. Dietary intake

    Time frame: baseline to 18 months

    Change in modified HEI score

  3. Physical Activity

    Time frame: baseline to 18 months

    Change in Sedentary Activity and Moderate/Vigorous Physical Activity using Godin Shephard

Study contacts

Contact information is provided by the study sponsor or research team.

Jerica Berge, PhD

CONTACT

[email protected]

Jerica M Berge, PhD, MPH

CONTACT

[email protected]

303-724-1938

Sponsors and collaborators

Lead sponsor

University of Colorado, Denver

Other

Collaborators

  • National Institutes of Health (NIH)

Registry information

Important dates

Study start
2022
Primary completion
2028
Study completion
2028
First posted
Feb 27, 2023
Registry last updated
May 8, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.