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OpenTrials
Completed

NCT Number: NCT01504230

Multi-joint Coordination Underlies Upright Balance Control in Elderly With Osteoporosis

Osteoporosis is a prevalent health concern among older adults and is associated with an increased risk of falls that can cause fracture, injury and even mortality. Identifying the factors related to falls occur within this population is essential for the development of effective regimes for fall prevention. The long-term objectives of this work are to ascertain the mechanisms for effectively controlling balance in seniors with osteoporosis and to provide a basis for developing fall prevention programs. The entire body's center of mass (CoM) is a critical indicator for balance control and the coordination among joints and muscles to control the CoM is still unclear. The aim1 of this study is to develop biomechanical models that control the entire body's center of mass (CoM) during upright quiet stance in seniors with osteoporosis. The aim2 of this study is to identify the mechanism to control the entire body's CoM after receiving a balance perturbation in seniors with osteoporosis. The findings of this research can provide needed information regarding the processes of balance control in this vulnerable osteoporosis population, and has the potential to be applied to individuals with other neuromuscular and orthopedic deficits.

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Key information

Age range

65 year–85 year

Sex eligibility

All sexes

Study type

Observational

Primary location

School & Graduate Institute of Physical Therapy College of Medicine, National Taiwan University

Taipei, Taiwan

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • for healthy older adults (OA)
  • can stand for 5 minutes and walk for 6 minutes independently
  • normal or corrected to normal vision
  • an age between 65-85 years
  • no osteoporosis (T-score above -2.5)
  • for osteoporosis participants (OP)
  • can stand for 5 minutes and walk for 6 minutes independently
  • normal or corrected to normal vision
  • an age between 65-85 years
  • no osteoporosis (T-score below -2.5)

Exclusion criteria

  • pregnant women
  • cancer diagnosis
  • sensory-motor deficits
  • the BMI is larger than 30 or smaller than 18

Sponsors and collaborators

Lead sponsor

National Taiwan University Hospital

Other

Registry information

Important dates

Study start
2011
Primary completion
2013
Study completion
2013
First posted
Jan 5, 2012
Registry last updated
Dec 16, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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