Multi Centre Study Comparing OsseoSpeed TX With OsseoSpeed

Inclusion criteria

• Provision of informed consent
• Female/male aged 18 years and over
• History of edentulism in the study area of at least 3 months
• In need for implant(s) replacing missing tooth/teeth in the maxilla
• Deemed by the investigator to be suitable for one stage surgery
• Deemed by the investigator to be suitable for loading after 10-12 weeks
• Deemed by the investigator as likely to present an initially stable implant situation.
• Deemed by the investigator to have a "functional" opposing dentition at the time of loading the implants.

Exclusion criteria

• Unlikely to be able to comply with study procedures, as judged by the investigator
• Uncontrolled pathological processes in the oral cavity
• Known or suspected current malignancy
• History of radiation therapy in the head and neck region
• History of chemotherapy within 5 years prior to surgery
• Systemic or local disease or condition that would compromise post-operative healing and/or osseointegration
• Uncontrolled diabetes mellitus
• Corticosteroids or any other medication that would compromise post-operative healing and/or osseointegration
• Present alcohol and/or drug abuse
• Current need for bone grafting and/or augmentation in the planned implant area
• Involvement in the planning and conduct of the study (applies to both Astra Tech staff and staff at the study site)
• Previous enrolment in the present study.
• Simultaneous participation in another clinical study, or participation in a clinical study during the last 6 months.