Skip to main content
OpenTrials
Completed

NCT Number: NCT03208647

Multi Center Case Control Study on Multiple Risk Factors of Aplastic Anemia

To ascertain the risk factors of AA in ZheJiang Province of China at the moment, especially the comprehensive multiple factors risks. The author conducted a case-control research included 338 AA cases and 1464 controls. Subjects were surveyed using same standard questionnaire including personal data, past histories of diseases, family history and histories of occupational and daily exposure to harmful substances. Single and multiple Logistic regression analyses were made using SPSS17.0 on the dates to study potential factors in the development of AA.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Aplastic Anemia Anemia Anemia, Aplastic Bone Marrow Diseases Bone Marrow Failure Disorders Hematologic Diseases Hemic and Lymphatic Diseases

Age range

1 year–65 year

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All the patients of AA group met a AA diagnostic criteria；The control group were chosen from other departments who were under acute infection (such as pneumonia), acute abdominal emergency (such as appendicitis), cataract surgery;
  • 1-65 years old, male or female;
  • Sign the informed consent.

Exclusion criteria

  • With myelodysplastic syndrome, leukaemia, multiple myeloma,megaloblastic anaemia, paroxysmal sleep hemoglobinuria disease blood disease, etc.
  • History of tumor, radiation or chemotherapy, once accept the immunological therapy, autoimmune diseases or allergic disease patients;
  • Patients with neurological diseases.

Treatment and study plan

AA or not

Other

to study their risk factors

Primary outcomes

  1. the items about daily Exposures

    Time frame: January 2014

    Whether living or working near chemical factory or ionizing radiation, whether living in newly decorated apartments/house, having pets/livestock

Secondary outcomes

  1. Individual Behaviours

    Time frame: January 2014

    Smoking (daily number of cigarettes )

  2. Occupational Exposures

    Time frame: January 2014

    the duration of exposure to harmful substance(including industrial glue）

  3. Individual Health Status

    Time frame: January 2014

    the time for the first onset of AA

  4. Family disease history

    Time frame: January 2014

    Whether having the same disease, other blood diseases, malignant tumor

Sponsors and collaborators

Lead sponsor

Shengyun Lin

Other

Registry information

Official study title

Multi Center Case Control Study on Multiple Risk Factors of Aplastic Anemia Based on EDC Data Management Platform

Acronym: MCSAA

Important dates

Study start
2003
Primary completion
2014
Study completion
2014
First posted
Jul 5, 2017
Registry last updated
Jul 5, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.