Skip to main content
OpenTrials
Completed

NCT Number: NCT05660629

Mulligan Mobilization in Rheumatoid Hand

The goal of this randomized-controlled study is to learn about the effectiveness of the Mulligan mobilization in rheumatoid hands. The main question it aims to answer are:

-Does mulligan mobilization reduce effusion in wrist joints with rheumatoid arthritis? Participants will take Mulligan mobilization application and active ROM exercises for their hands. Researcher will compare treatments group ith sham mobilization.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Rheumatoid Arthritis Arthritis Arthritis, Rheumatoid Autoimmune Diseases Connective Tissue Diseases Immune System Diseases Joint Diseases Musculoskeletal Diseases Rheumatic Diseases Skin and Connective Tissue Diseases

Age range

30 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Ahi Evran University

Kırşehir, Turkey (Türkiye)

About this study

Rheumatoid arthritis (RA) is a systemic disease that can lead to chronic pain, bone and soft tissue damage, and disability retirement. Alleviating pain and maintaining joint range of motion in RA are important for reducing disability. Joint mobilizations are manual therapy techniques used to increase range of motion and reduce pain. The aim of this study is to investigate the effects of rheumatoid hand exercise and protective approach and joint mobilization applications on pain, functional status and quality of life.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Having been diagnosed with RAS according to ACR and EULAR criteria,
  • Being under the control of a physiatrist for at least 1 year,
  • Have not had any upper extremity surgery in the last 6 months
  • Have the cognitive capacity to understand commands,
  • Not to be involved in any other rehabilitation program or study,

Exclusion criteria

  • Presence of soft tissue injury and chronic bone damage in the hand,
  • Presence of acute inflammation in any joint in the previous week,
  • Presence of a degenerative or non-degenerative neurological condition that causes a change in pain perception,

Treatment and study plan

Mulligan mobilization

Other

Mobilization with movement (MWM) is the concurrent application of sustained accessory mobilization applied by a therapist and an active physiological movement to end range applied by the patient. Passive end-of-range overpressure, or stretching, is then delivered without pain as a barrier.

Primary outcomes

  1. Joint activity

    Time frame: 6 weeks

    Primary outcomes included the automated quantification (Q) of joint activity using color Doppler pixel count calculations (% hyperemia/blood flow activity score within an inflamed joint: color Q-Doppler MCP/region)

  2. Amount of hypertrophia and effusion in wrist joints

    Time frame: 6 weeks

    Synovial fluid (area of hypertrophy and effusion, mm2: synovial fluid MCP/region)

  3. Distance in wrist joints

    Time frame: 6 weeks

    the radiographic distance (mm) between the MCP or interphalangeal bone space (joint space MCP/region)

  4. DAS-28

    Time frame: 6 weeks

    High disease activ ity >5.1, low disease activity ≤ 3.2, remission ≤ 2.6

Secondary outcomes

  1. Determining the state of pain after treatment

    Time frame: 6 weeks

    Pain will be assessed using the Mcgill-Melzack Pain Questionnaire

  2. Grip force

    Time frame: 6 weeks

    Hand grip strength will be measured with a pinch meter and a dynamometer

  3. Range of Motion

    Time frame: 6 weeks

    Range of Motion will be measured with goniometer

  4. Post-treatment status of disease-related quality of life

    Time frame: 6 weeks

    Quality of life was assessed using the Rheumatoid Arthritis Quality of Life (RAQoL).

  5. Physical, social, and emotional well-being in RA

    Time frame: 6 weeks

    Arthritis Impact Measurement Scales (AIMS)

Sponsors and collaborators

Lead sponsor

Kirsehir Ahi Evran Universitesi

Other

Registry information

Official study title

Comparison of the Effects of Exercise and Protective Approach in the Rheumatoid Hand and Joint Mobilization Applications on Pain, Functional Status and Quality of Life

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
Dec 21, 2022
Registry last updated
Dec 17, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.