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NCT Number: NCT07246122

MRI-Guided Dynamic Support System for Scoliosis Correction

This prospective pilot study evaluates the feasibility and effectiveness of an MRI-guided dynamic support system (MRI-DSS) for rapid, quantitative correction of adolescent idiopathic scoliosis (AIS). The system uses MRI-compatible air padding supports and programmable pneumatic control to apply and adjust corrective forces in real time. AIS patients underwent MRI-guided bracing, with Cobb angles and biomechanical parameters measured at each pressure level.

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Key information

Conditions

Adolescent Idiopathic Scoliosis Bone Diseases Musculoskeletal Diseases Scoliosis Spinal Curvatures Spinal Diseases

Age range

10 year–16 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

The Hong Kong Polytechnic University

Tsim Sha Tsui, Kowloon, Hong Kong

Location status: Recruiting

Location contact

Joanne Yip, PhD

CONTACT

27664848

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age: 10-16 years
  • Diagnosis: Adolescent idiopathic scoliosis (Cobb angle 10-25°)
  • No prior spinal surgery or other orthopedic conditions
  • Able to provide informed consent
  • Risser sign 0-5

Exclusion criteria

  • Age <10 or >16 years
  • Cobb angle <10° or >25°
  • History of spinal surgery or other spine disorders
  • Contraindications to MRI

Treatment and study plan

MRI-guided Dynamic Support System

Device

MRI-compatible pneumatic support system with customized padding inserted into the brace, used for image-guided adjustment of corrective pressure during MRI scanning

Primary outcomes

  1. Change in Cobb angle

    Time frame: baseline

    degrees measured by MRI

  2. Time to achieve target correction

    Time frame: immediately after the intervention

    measured in minutes

Secondary outcomes

  1. Contact area and force distribution

    Time frame: immediately after the intervention

    measured by 3D MRI reconstruction

Study contacts

Contact information is provided by the study sponsor or research team.

Joanne Yip, PhD

CONTACT

[email protected]

27664848

Raymond Tong, PhD

CONTACT

[email protected]

39438454

Sponsors and collaborators

Lead sponsor

Chinese University of Hong Kong

Other

Collaborators

  • The Hong Kong Polytechnic University

Registry information

Official study title

MRI-Guided Dynamic Support System for Scoliosis Correction (MRI-DSS)

Important dates

Study start
2023
Primary completion
2027
Study completion
2027
First posted
Nov 24, 2025
Registry last updated
Nov 24, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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