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OpenTrials
Completed

NCT Number: NCT04775420

MPV and NLR as Predictors of SBP Diagnosis

The aim of the study is to investigate the clinical utility of mean platelet volume (MPV) and neutrophil to lymphocyte ratio (NLR) as diagnostic markers for spontaneous bacterial peritonitis (SBP).

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Key information

Conditions

Spontaneous Bacterial Peritonitis

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Sohag Faculty of Medicine

Sohag, 82524, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Decompensated liver cirrhosis ascetic patients.

Exclusion criteria

  • Immunocompromised patients.
  • Patients who had received antibiotics before hospital admission.
  • Patients on anticoagulant medications, NSAIDs, or oral contraceptive drugs.
  • Patients with heart failure, diabetes mellitus, hypertension, hyperlipidemia, peripheral vascular disease, hematological disorders, and neoplastic disorders and patients with clinically overt hypothyroidism or hyperthyroidism or with clinically and laboratory-evident autoimmune diseases.

Treatment and study plan

Measurement of mean platelet volume (MPV) and blood neutrophil to lymphocyte ratio (NLR)

Diagnostic Test

MPV and NLR are easily accessible and inexpensive tests

Primary outcomes

  1. The utility of MPV as non-invasive predictor of SBP

    Time frame: 1 year

    It will be measured from CBC

  2. The utility of NLR as non-invasive predictor of SBP

    Time frame: 1 year

    It will be measured from CBC

Sponsors and collaborators

Lead sponsor

Sohag University

Other

Registry information

Official study title

Mean Platelet Volume (MPV) and Neutrophil to Lymphocyte Ratio (NLR) as Predictors of Spontaneous Bacterial Peritonitis in Cirrhotic Patients

Important dates

Study start
2020
Primary completion
2022
Study completion
2022
First posted
Mar 1, 2021
Registry last updated
Jan 23, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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