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OpenTrials
Completed

NCT Number: NCT00581542

Moxifloxacin vs. Polytrim for Conjunctivitis

The purpose of the study is to compare the effect of Polytrim Ophthalmic Solution and Moxifloxacin Ophthalmic Solution in treating your child's pink eye. Both these medications are approved by the Food and Drug Administration, for treatment of conjunctivitis. This study will investigate if both of the medications are equally good.

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Key information

Conditions

Conjunctivitis Conjunctival Diseases Eye Diseases

Age range

1 year–18 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

University of Rochester

Rochester, New York, 14642, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 1 - 18 years of age with presumed bacterial conjunctivitis.

Exclusion criteria

  • Previous antibiotics or to receive systemic antibiotic.

Treatment and study plan

moxifloxacin

Drug

1-2 drops three times a day for 8-10 days.

polytrim

Drug

1-2 drops four times a day for 8-10 days.

Primary outcomes

  1. Number of Participants With Normal Physical Examination of the Eye

    Time frame: 10 days

Secondary outcomes

  1. Number of Participants With a Negative Bacterial Culture

    Time frame: 10 days

    Conjunctival swab specimens were inoculated onto tryptic soy agar with 5% sheep blood and GC II agar supplemented with hemoglobin and isovialex with incubation at 35 degrees C in ambient air supplemented with 5% carbon dioxide for 48 hours. S pneumoniae, H influenzai and M Catarrhalis were identified.

Sponsors and collaborators

Lead sponsor

University of Rochester

Other

Registry information

Official study title

A Single Blinded Clinical Trial Comparing Polytrim Ophthalmic Solution and Moxifloxacin Ophthalmic Solution for Treatment of Conjunctivitis.

Important dates

Study start
2007
Primary completion
2009
Study completion
2012
First posted
Dec 27, 2007
Registry last updated
Jan 18, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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