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NCT Number: NCT06802094

Movement Strategies During Balance Tasks in Children With and Without Developmental Coordination Disorder

The main objective of the study is to gain insights in how children learn a balance task and whether there is a difference between children with and without Developmental Coordination Disorder. Furthermore, the investigators are interested in the brain activity of these children while learning this new balance task.

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Key information

Age range

7 year–12 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Hasselt Univeristy, Faculty of Rehabilitation Sciences

Diepenbeek, Limburg, 3590, Belgium

Location status: Recruiting

Location contact

Evi Verbecque, Prof. Dr.

SUB_INVESTIGATOR

Katrijn Klingels, Prof. Dr.

PRINCIPAL_INVESTIGATOR

Maja Van Grinderbeek

CONTACT

[email protected]

+32476332092

Maja Van Grinderbeek, Msc

SUB_INVESTIGATOR

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

For children with DCD

  • Children with the clinical diagnosis of Developmental Coordination Disorder (DCD) based on criteria of the DSM-5 (APA, 2013), diagnosed by a pediatrician.
  • Children who have no formal diagnosis are evaluated by the research team using the diagnostic criteria as outlined in the inclusion criteria, these children will be included as "suspected of having DCD"
  • Balance problems need to be present and objectified with the Balance Evaluation Systems Test for Children, second edition (Kids-BESTest-2). (total score below 80%)

For children without DCD

  • Total score at or below the 25th percentile on the Movement Assessment Battery for children, second edition
  • Normal postural control, objectified by the Kids-BESTest-2 (score at or above 80%)
  • Match with children with DCD based on their sex, age and potential comorbidities.

Exclusion criteria

Presence of:

  • Intellectual problems
  • Visual problems
  • Vestibular problems
  • Neurological conditions
  • Not able to follow instructions due to behavioral problems
  • Refuse to participate

Treatment and study plan

Single-session balance intervention in virtual reality

Other

Single-session balance intervention (30 minutes) in a virtual reality environment, the Gait Real-time analysis Interactive Lab (GRAIL) or the Computer Assisted Rehabilitation Environment (CAREN) in children with and without Developmental Coordination Disorder (Motek Medical, The Netherlands).

Primary outcomes

  1. Changes in the center of mass velocity and acceleration after a single-training session in VR and after a one-week retention

    Time frame: Baseline, after 30 minutes intervention, one week

    Measurement of the movement strategies used by children with and without Developmental Coordination Disorder (DCD) during a balance task. The movement strategies are measured by looking at the center of mass velocity and acceleration during this balance task. The goal is to: (1) investigate whether there is a difference in the used strategies between baseline and after a single training session of 30 minutes; (2) see whether the changes stay present after a one-week retention; (3) see whether there are differences between children with and without DCD.

Secondary outcomes

  1. Hemodynamic response in cortical brain regions during balance tasks

    Time frame: Baseline, one week

    Measurement of the changes in Oxy- and Deoxyhemoglobin concentrations (μmol/l) (baseline vs task condition), with the use of Functional Near-Infrared Spectroscopy (fNIRS), during the execution of balance tasks. The regions of interest are determinded based on the evidence of brain areas needed for postural control tasks in healthy individuals, and affected brain regions in children with DCD in a variety of tasks (frontal and parietal regions).

    The goal is to: (1) determine whether brain activity patterns can be an explanation of the movement strategies used during the single-training session; (2) determine the test-retest reliability of fNIRS during balance tasks in children.

    The NIRSport 2 (NIRx Medical Technologies, GE) with continuous wave imaging (760nm;850nm) is used.

  2. Score on a comprehensive postural control measurement, Kids-BESTest-2

    Time frame: Baseline

    Score on the Balance Evaluation Systems Test for Children, second edition. The test consists of 6 domains. A score below 80% is the cut-off which corresponds to a postural control problem. The scores give an idea in which domain of postural control the problems are present.

Other outcomes

  1. Score on a general motor scale, Movement Assessment Battery for Children, second edition

    Time frame: Baseline

    The MABC-2 consists of 3 domains (manual dexterity, aiming and catching, balance) with a total of 8 tasks. The test gives a general idea about the motor develompment of children on different domains.

Study contacts

Contact information is provided by the study sponsor or research team.

Katrijn Klingels

CONTACT

[email protected]

Maja Van Grinderbeek

CONTACT

[email protected]

+32476332092

Sponsors and collaborators

Lead sponsor

Hasselt University

Other

Registry information

Official study title

Case-Control Research of the Movement Strategies Used During Balance Tasks in Children With and Without Developmental Coordination Disorder

Important dates

Study start
2025
Primary completion
2027
Study completion
2027
First posted
Jan 30, 2025
Registry last updated
Sep 16, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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