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NCT Number: NCT06945185

Motor Imagery Training for Upper Limb Functional Strength in Chronic Stroke Patients

Stroke is a leading cause of upper extremity deficits worldwide. Persistent upper extremity dysfunction affects many post stroke patients and is strongly associated with decreased activities of daily living and poor quality of life.

There is accumulating evidence of a cross-over effect with training of one limb that slightly increase strength and coordination in contralateral untrained limb through neurological adaptations.

One of rehabilitation that is beneficial for stroke patient is motor imagery, a mental rehearsal of a movement that does not include physical movement has been shown to enhance upper limb function.

Evidence demonstrate that MI not only activates motor cortical and subcortical regions but also induces plastic change in motor networks and modulates synaptic activity at spinal level.

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Key information

Age range

45 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Foundation University College of Physical Thrapy

Islamabad, 44000, Pakistan

Location status: Recruiting

Location contact

Sana Khalid, MS-NMPT

CONTACT

[email protected]

+92 344-4218174

About this study

OBJECTIVE:

The objectives of this study are:

  • To improve upper limb functional strength.
  • To improve the upper limb coordination.
  • To improve upper limb functional improvement.

HYPOTHESIS

Alternate Hypothesis:

There will be statistically significant difference in effects of motor imagery technique combined with conventional physical therapy and in comparison to conventional physical therapy alone on upper limb functional strength, coordination and functional improvement in chronic stroke. (p<0.05).

Null Hypothesis:

There will be no statistically significant difference in effects of motor imagery technique combined with conventional physical therapy and in comparison to conventional physical therapy alone on upper limb functional strength, coordination and functional improvement in chronic stroke. (p>0.05).

Research Design: Experimental study. Randomized Control Trial

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Stroke duration 6 months onwards (chronic stroke).
  • age 45 years and above.
  • Both genders.
  • Access cognitive function score > 24 on MoCA.

Exclusion criteria

  • Patients with any comorbidity, previous surgery and congenital anomly.
  • Patient with any fracture/ MSK disorders.
  • Score 3 or more on Modified Ashworth scale.
  • Patients with hearing impairments

Treatment and study plan

Intervention Group A Conventional Physical Therapy

Procedure

Active Range of Motion Exercises: (5-10 reps with 2 sets) Finger bends, finger spreads, finger to thumb opposition, thumb to palm stretches, palm up and down, wrist rotation, wrist bends, elbow bends, shoulder shrugging and shoulder rotation.

Strengthening Exercises: (10-15 reps 2 sets weight 500 ml to 1L water bottle). Finger pinch, power grip, finger spread, pushing movement, wrist curls, roll and squeeze, bicep curls, side arm raise, lifting objects to a height, pulling resistance band.

Coordination Exercises: (10-15 reps 2 sets) finger to finger, finger to doctor's finger, finger to nose, holding and lifting coins, buttoning, holding and lifting coins, alternate hand movement, closing and opening hand.

Intervention Group B Motor Imagery with Conventional Physical Therapy

Procedure
  • Subjects will be asked to sit comfortably on a chair with a backrest. A Quiet environment is ensured for proper concentration of subject .Take deep breaths for 2-3 min to relax.
  • Subjects will be asked to close their eyes and imagine the training scene for each task for 5 min while listening to the therapist 's voice describing the motion.
  • The non-paralysis part of the body's movement was imagined first and then the movement of the paralysis part was imagined.
  • Upon completion of the mental practice for the first activity, the subject will be given a comfortable break.

Motor Imagery Training:

Week 1-2: Approaching and holding a cup, turning book pages and grasping pencil to write.

Week 3-4: wiping desk, turning door handle and drinking water from cup. Week 5-6: pressing light switch on and off, turning faucet and putting card in wallet.

Week 7-8: folding towel, brushing teeth and brushing hair. Imagine for 30 sec 2-3 repetitions.

Primary outcomes

  1. FUNCTIONAL STRENGTH

    Time frame: 8 weeks

    FUNCTONAL STRENGTH WILL BE ASSESSED USING WOLF MOTOR FUNCTION TEST

  2. Coordination

    Time frame: 8 weeks

    The Action Research Arm Test (ARAT) will be used to assess upper extremity performance

Study contacts

Contact information is provided by the study sponsor or research team.

AYESHA ASIF, DPT

CONTACT

[email protected]

+92 316-5314207

Sponsors and collaborators

Lead sponsor

Foundation University Islamabad

Other

Registry information

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Apr 25, 2025
Registry last updated
Apr 25, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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