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NCT Number: NCT07549087

Motor Imagery Reaction Time in Individuals With Paraplegic Spinal Cord Injury

Individuals aged 18-65 years who have been clinically diagnosed with spinal cord injury and have developed paraplegia will be included in the study. Demographic and clinical data of the participants, including age, sex, height, weight, etiology of injury, level of injury, duration of injury, and comorbidities, will be recorded. In addition, disease-specific characteristics such as ambulation status, wheelchair use, presence of incontinence, and presence and severity of pain will be assessed. For the healthy control group, demographic data including age, sex, height, weight, and comorbidities will be recorded.

Motor imagery performance of the participants will be evaluated using a computer-based left/right judgment task. In this context, both upper extremity (hand) and lower extremity (foot) images will be used to record reaction time (motor imagery reaction time) and accuracy rate. All tests will be performed under standardized conditions, in a seated position, and using the same device.

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Key information

Conditions

Spinal Cord Injuries Central Nervous System Diseases Nervous System Diseases Spinal Cord Diseases Trauma, Nervous System Wounds and Injuries

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Istanbul Physical Medicine and Rehabilitation Trainig and Research Hospital

Istanbul, Bahcelievler, 34100, Turkey (Türkiye)

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Aged between 18 and 65 years
  • Clinically diagnosed with spinal cord injury
  • Presence of paraplegia
  • Injury duration of at least 3 months
  • Medically stable condition
  • Ability to understand and follow study instructions
  • Ability to complete the computer-based left/right judgment task
  • Willingness to participate and provide written informed consent
  • For the healthy control group: age- and sex-compatible individuals without a history of neurological or major musculoskeletal disease, willing to participate and provide written informed consent

Exclusion criteria

  • Tetraplegia
  • History of other neurological disorders that may affect motor imagery performance
  • Severe cognitive impairment or communication problems preventing proper participation
  • Severe visual impairment uncorrected by glasses or lenses
  • Upper or lower extremity musculoskeletal disorders, deformities, or recent injuries that may affect task performance
  • Severe psychiatric disorder
  • Uncontrolled pain or acute medical condition at the time of assessment
  • Current participation in another interventional clinical study

Treatment and study plan

No intervention

Other

No intervention

Primary outcomes

  1. Motor Imagery Reaction Time - Upper Extremity

    Time frame: Baseline

    Reaction time (in milliseconds) required to correctly identify left or right hand images in a computer-based motor imagery task. Longer reaction times indicate impaired motor imagery processing.

  2. Motor Imagery Reaction Time - Lower Extremity

    Time frame: Baseline

    Reaction time (in milliseconds) required to correctly identify left or right foot images. Higher values indicate slower motor imagery performance.

Secondary outcomes

  1. Functional Independence

    Time frame: Baseline

    Functional independence will be assessed only in individuals with spinal cord injury. Scores range from 0 to 100, with higher scores indicating greater independence.

  2. Hospital Anxiety and Depression Scale - Anxiety Subscale (HADS-A)

    Time frame: Baseline

    Scores range from 0 to 21, with higher scores indicating greater anxiety.

  3. Hospital Anxiety and Depression Scale - Depression Subscale (HADS-D)

    Time frame: Baseline

    Scores range from 0 to 21, with higher scores indicating greater depressive symptoms.

Sponsors and collaborators

Lead sponsor

Istanbul Physical Medicine Rehabilitation Training and Research Hospital

Other Gov

Registry information

Official study title

Upper and Lower Extremity Motor Imagery Reaction Time in Individuals With Paraplegic Spinal Cord Injury: A Comparative Study With Healthy Controls

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Apr 23, 2026
Registry last updated
Apr 23, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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