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NCT Number: NCT06138613

Motion Delos: An Open Label Safety and Efficacy of Tradipitant in Participants Affected by Motion Sickness

An open label study to investigate the safety and efficacy of tradipitant in participants affected by motion sickness during travel

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Conditions

Motion Sickness Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 3

Primary location

Santa Monica Clinical Trials

Santa Monica, California, 90404, United States

About this study

This is an open label study to investigate the efficacy and safety of tradipitant in motion sickness affected male and female participants during events historically known to cause motion sickness.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • History of Motion Sickness
  • Age 18-75

Exclusion criteria

  • Nausea-inducing disorder other than motion sickness
  • BMI > 40
  • History of intolerance and/or hypersensitivity to Neurokinin-1 Receptor antagonists

Treatment and study plan

Tradipitant

Drug

Oral Capsule

Primary outcomes

  1. Safety and tolerability of tradipitant as measured by reporting of adverse events (AEs).

    Time frame: through study completion, approximately 1 year

    Safety will be monitored using clinical measures, vital signs, blood chemistry, hematology, urology, and ECGs.

Sponsors and collaborators

Lead sponsor

Vanda Pharmaceuticals

Industry

Registry information

Official study title

Motion Delos: An Open Label Study to Investigate the Safety and Efficacy of Tradipitant in Participants Affected by Motion Sickness During Travel

Important dates

Study start
2023
Primary completion
2027
Study completion
2027
First posted
Nov 18, 2023
Registry last updated
Apr 16, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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