Kafrelsheikh University
Kafr ash Shaykh, Kafrelsheikh, 33516, Egypt
NCT Number: NCT07012590
This study aimed to compare the analgesic efficacy between morphine and dexmedetomidine as adjuvants to bupivacaine in ultrasound-guided erector spinae plane block for open subcostal renal surgeries.
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Notify Me20 year–65 year
All sexes
Interventional
Not applicable
Kafr ash Shaykh, Kafrelsheikh, 33516, Egypt
The postoperative pain that occurs because of the wide flank incision ranges from a moderate to severe intensity and, in some patients, can become chronic.
The erector spinae plane block (ESPB) is a novel interfascial plane technique, aiming to block the dorsal and ventral rami of the spinal nerves to provide visceral and somatic multi-dermatomal analgesia of the cervical, thoracic, and lumbar levels.
Adjuvants to local anesthetics, such as morphine and dexmedetomidine, can be used to improve the quality and duration of peripheral nerve block effects.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Patients received erector spinae plane block with morphine 2 mg as an adjuvant to bupivacaine 30 ml 0.25%.
Patients received erector spinae plane block with dexmedetomidine 100 µg as an adjuvant to bupivacaine 30 ml 0.25%.
Patients received erector spinae plane block with bupivacaine 30 ml 0.25% only.
Time frame: 24 hours postoperatively
The degree of pain was assessed using the Visual analogue scale (VAS) [where (0 = no pain and 10 = severe pain)]. VAS was evaluated at 0, 2, 4, 6, 8, 12, 18, and 24 hours postoperatively.
Time frame: Intraoperatively
Duration of sensory block was assessed.
Time frame: 48 hours postoperatively
Time to first rescue analgesia was assessed from the end of surgery till first dose of pethidine administrated.
Time frame: 48 hours postoperatively
If the Visual analogue scale (VAS) is ≥ 3, intravenous pethidine was given (0.5mg/kg).
Time frame: 48 hours postoperatively
Heart rate was recorded at baseline, after injection then every 30 min till the end of surgery and after surgery at 0, 2, 4, 6, 8, 12, 24 and 48 h.
Time frame: 48 hours postoperatively
Mean arterial pressure was recorded at baseline, after injection then every 30 min till the end of surgery and after surgery at 0, 2, 4, 6, 8, 12, 24 and 48 h.
Kafrelsheikh University
Other
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