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OpenTrials
Completed

NCT Number: NCT00575497

More Frequent Dialysis (>3 Treatments Per Week)

The study compares the benefits of short daily hemodialysis six days a week, nocturnal (night time) hemodialysis six days a week, every other day and every other night hemodialysis to traditional three days a week hemodialysis.The hypothesis is that increasing hemodialysis treatment time and/or frequency will improve outcomes.

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Key information

Conditions

End Stage Renal Disease Chronic Disease Chronic Kidney Disease Disease Attributes Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Kidney Diseases Kidney Failure, Chronic Male Urogenital Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms Renal Insufficiency Renal Insufficiency, Chronic Urogenital Diseases Urologic Diseases

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Satellite Healthcare, Inc., Mountain View, California, United States

Loading trial locations.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Stable vascular access, i.e., lack of needling difficulties and stable flow rates. Accesses will include fistulae, grafts, catheters and ports.
  • 18 years of age.
  • History of compliance with a dialysis treatment schedule, or if a new patient, express a willingness to be compliant with a treatment schedule.
  • Plan to continue care and follow-up at the investigational site.
  • Able to sign the informed consent and other relevant documents.

Exclusion criteria

  • History of poor compliance with thrice (or twice) weekly dialysis schedules as manifested by more than three unexplained missed treatments in the past six (6) months.
  • Pregnancy.
  • Intravenous drug abuser.
  • Expects to receive a transplant or transfer to another facility within six months of entering the study.

Treatment and study plan

More frequent hemodialysis

Procedure

Six Day per week short daily hemodialysis

Conventional Hemodialysis

Procedure

3 days per week short daily hemodialysis

Primary outcomes

  1. Hospitalization days per year

    Time frame: Ongoing

Secondary outcomes

  1. Nutritional Status measured by Subjective Global Assessment

    Time frame: Ongoing

  2. Anemia, measured by erythropoetin dose

    Time frame: Ongoing

  3. Control of hypertension, as measured by number of antihypertensive tablets taken per day

    Time frame: Ongoing

  4. Control of hyperphosphatemia, as measured by number of phosphate binder tablets taken per day

    Time frame: Ongoing

Sponsors and collaborators

Lead sponsor

Satellite Healthcare

Other

Registry information

Official study title

Study of Clinical Outcomes of More Frequent Hemodialysis

Acronym: MFD

Important dates

Study start
2005
Primary completion
2012
Study completion
2012
First posted
Dec 18, 2007
Registry last updated
Apr 19, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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