Cleveland Clinic
Cleveland, Ohio, 44125, United States
NCT Number: NCT04660955
In this study, a total of 219 subjects from the MOON nested cohort will be studied at CCF, Vanderbilt and OSU, Table 1. Among them, some will have added MRI during their 10-year visit for the MOON study. Some subjects who finished their 10-year visit for the MOON Onsite study already will be called back to have MRI. PROMs and other information of these subjects will be collected through the MOON study.
Interested in participating?
Request Info22 year–45 year
All sexes
Observational
Cleveland, Ohio, 44125, United States
In this study, a total of 219 subjects from the MOON nested cohort will be studied at CCF, Vanderbilt and OSU, Table 1. Among them, some will have added MRI during their 10-year visit for the MOON study. Some subjects who finished their 10-year visit for the MOON Onsite study already will be called back to have MRI. PROMs and other information of these subjects will be collected through the MOON study.
In addition, 30 age-, sex- and BMI-matched control subjects (10 from each site) will be recruited and scanned for MRI. PROMs (KOOS, IKDC, Marx, SF-36) will be collected from these controls.
Among the 10 controls recruited locally at CCF, five will also travel to OSU and Vanderbilt to be scanned at the other two sites for cross-validation among the three sites. There will be a separate consent for the 5 controls that will be traveling to each of the 3 sites for the scans. The remaining 25 controls will be tested at only their local site.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
90 minute MRI of the knees
Time frame: At 10-years after ACL reconstruction
Quantitative MRI will be used to quantify cartilage health. Specifically, cartilage MR T1rho and T2 relaxation times will be quantified for cartilage of the knee that had ACL reconstruction, and compared to the contralateral uninjured knee.
Time frame: At 10-years after ACL reconstruction
Pain score (0-100) evaluated using Knee injury and Osteoarthritis Outcome Score (KOOS)
The Cleveland Clinic
Other
Imaging Post-traumatic Osteoarthritis 10-years After ACL Reconstruction
Acronym: MRI
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT06957444
Allergic Contact Dermatitis, Arthritis
Morgantown, West Virginia, United States
View Trial DetailsNCT05752032
Arthritis, Joint Diseases
Adelaide, South Australia, Australia
View Trial DetailsNCT03681977
Arthritis, Joint Diseases
Montreal, PQ, Canada
View Trial DetailsNCT03484325
Arthritis, Joint Diseases
Houston, Texas, United States
View Trial Details