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OpenTrials
Completed

NCT Number: NCT05684120

Mood Lifters for Undergraduates

Large-scale, effective, low-cost, and evidence-based programs that can nimbly translate new research discoveries into prevention and care for psychosocial-based problems are urgently needed since the vast majority of people who need evidence-based care do not receive it.

The purpose of this randomized control trial is to investigate the feasibility and efficacy of a Mood Lifters group template specifically for undergraduate students. Mood Lifters is an effective peer-led program that improves or maintains mental health. It seeks to help people enhance pleasure, engagement, and meaning in their lives while minimizing depression, fear, loneliness, and other negative feelings via a proprietary peer-based program that offers weekly meetings and other flexible support options. One obstacle to providing mental health care in the US is that it is costly to provide one-on-one therapy by a licensed professional. This is particularly true in large group settings with limited resources (counseling centers) and a large need for mental health care, like universities.

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Key information

Conditions

Depression Anxiety Anxiety Disorders Behavior Behavioral Symptoms Mental Disorders Mental Health Wellness 1 Mood Disorders Stress

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Michigan

Ann Arbor, Michigan, 48103, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion:

  • undergraduate students
  • at least 18 years of age

Exclusion criteria

include:

  • active suicidal thoughts or behavior
  • active psychosis
  • borderline personality disorder
  • active mania
  • unwillingness to attend all sessions or treatment types (e.g., unwillingness to attend remote)
  • non-undergraduate students.

Treatment and study plan

Mood Lifters for Undergraduates

Behavioral

Participants will need to attend 14 hour-long virtual weekly meetings on Zoom that focus on helpful mental health strategies and skills. Participants will be encourage to practice what they learn at home in order to improve their mood or mental wellness.

Other names: Mood Lifters for College Students

Primary outcomes

  1. Patient Health Questionnaire - 9

    Time frame: through study completion, an average of 1 year

    Assesses Depressive Symptoms (Range 0-27; higher scores indicate more significant symptoms of depression)

  2. Generalized Anxiety Disorder - 7

    Time frame: through study completion, an average of 1 year

    Assesses Anxiety Symptoms (Range 0-21; higher scores indicate more significant symptoms of anxiety)

Sponsors and collaborators

Lead sponsor

University of Michigan

Other

Registry information

Official study title

Mood Lifters for Undergraduates Project

Acronym: ML-UP

Important dates

Study start
2023
Primary completion
2025
Study completion
2025
First posted
Jan 13, 2023
Registry last updated
Dec 10, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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