Monitoring of Hydration Status in Chronic Hemodialysis Patients

Background Maintaining fluid balance is one of major challenges of the dialysis therapy. It includes, in particular, the management of "dry body mass". We postulated that simple measurement of subscapular skinfold thickness before and after hemodialysis could help monitor hydration status in chronic dialysis patients.

Aim of the study The aim of the study was to compare the conventional methods of monitoring hydration status during hemodialysis with an assessment of skin fold thickness.

Materials and Methods 50 participants (21 F, 29 M; age 60 ±15 years) were enrolled. Directly before the hemodialysis session the following parameters were measured: body composition with bioimpedance spectroscopy, skinfold thickness in subscapular area with standardized caliper and blood tests: blood count, urea, n-terminal pro B-type natriuretic peptide (nt-proBNP) and pro-adrenomedullin (pro-ADM). The procedures were repeated at the end of three consecutive hemodialysis sessions.

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Key information

Conditions

Hemodialysis Chemically-Induced Disorders Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Kidney Diseases Kidney Failure Male Urogenital Diseases Metabolic Diseases Nutritional and Metabolic Diseases Overhydration Poisoning Renal Insufficiency Urogenital Diseases Urologic Diseases Water Intoxication Water-Electrolyte Imbalance

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Central University Hospital

Lodz, 92-213, Poland

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

chronic hemodialysis for at least 3 months

Exclusion criteria

severe mental disabilities, poor compliance, any acute infection, instability of the cardiovascular hemodynamic condition

Treatment and study plan

dialysisis with and without glucose in the dialysis

Procedure

there were assessed three consecutive hemodialysis sessions

Primary outcomes

changes in overhydration

Time frame: From enrollment to one week

Sponsors and collaborators

Lead sponsor

Medical University of Lodz

Other

Registry information

Official study title

Measurement of Skinfold Thickness in Subscapular Area to Monitor Hydration Status in Chronic Hemodialysis Patients

Important dates

Study start: 2021
Primary completion: 2023
Study completion: 2024
First posted: Jan 29, 2025
Registry last updated: Jan 29, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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