Skip to main content
OpenTrials
Completed

NCT Number: NCT02336191

Monitoring Living Donor Liver Functions by Thromboelastometry

A prospective Observational study including 50 living donor liver transplant recipients to monitor the graft functions through thromboelastometry

Completed

Looking for future studies?

Notify Me

Key information

Conditions

THROMBELASTOGRAPHY and Liver Graft Functions

Age range

18 year–60 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Gastroenerology Surgical Center - Liver transplantation program

Al Mansurah, Dakahlia Governorate, 35516, Egypt

About this study

This is a prospective observational study Includes 50 living donor liver transplant recipients performed in gastroenterology surgical center - Mansoura University liver transplantation program.

Study period: from June 2014 to May 2015 The early post-operative graft functions will be correlated with concomitant monitored thromboelastometric (TEM) parameters derived from a ROTEM Delt device

TEM Samples will be collected at the following times:

Pre-transplant 10 minutes post portal declamping at ICU admission Morning of Days from 1 to 7 Laboratory data relevant to graft functional status will be collected at the same times.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Living donor liver transplant recipients successively performed in the liver transplantation program - Mansoura university

Exclusion criteria

  • Non

Treatment and study plan

Living donor liver transplantation

Procedure

living donor liver transplantation

Primary outcomes

  1. r (correlation coefficient) between clot firmness time at 20 minutes, clotting time and INR

    Time frame: 20 minutes after starting the TEG test

    Both blood sample for INR and other lab test and the sample for TEG will be simultaneously drawn from the arterial line for reading of days 0,1 and 2 then from the CVP for the rest of the study readings

Secondary outcomes

  1. r (correlation coefficient) between clotting time , clot firmness time at 20 minutes and serum bilirubin

    Time frame: 20 minutes after the start of the TEG test

  2. r (correlation coefficient) between clotting time , clot firmness time at 20 minutes and serum SGPT

    Time frame: 20 minutes after the start of the TEG test

Sponsors and collaborators

Lead sponsor

Mansoura University

Other

Registry information

Official study title

Monitoring Post-transplant Living Donor Liver Functions by Thromboelastometry. A Prospective Observational Study.

Acronym: TGF

Important dates

Study start
2014
Primary completion
2015
Study completion
2015
First posted
Jan 12, 2015
Registry last updated
Mar 28, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.