Monitoring Hypertensive Patients's Cerebral Oxygen Saturation

The purpose of this study is to determine whether there is a significant decrease in cerebral oxygen saturation in hypertensive patients undergoing major abdominal surgery and their correlation with standard monitoring parameters.

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Key information

Conditions

Surgical Complications From General Anesthesia Brain Diseases Brain Ischemia Cardiovascular Diseases Central Nervous System Diseases Cerebral Anoxia Cerebral Ischemia Cerebrovascular Disorders Hypertension Hypoxia Hypoxia, Brain Nervous System Diseases Pathological Conditions, Signs and Symptoms Signs and Symptoms Signs and Symptoms, Respiratory Vascular Diseases

Age range

30 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology

Wuhan, Hubei, 430030, China

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

patients have hypertension more than 3 year,whether well-controlled or uncontrolled,
scheduled for major abdominal surgery for at least 2 h
under general anesthesia
American Society of Anesthesiologists（ASA）physical status : II ~ III
Age > 30

Exclusion criteria

pre-existing cerebral pathology for example episodes of cerebral ischemia or stroke;
ASA physical status >IV
hepatic failure
renal failure
preoperative Mini-Mental State Examination (MMSE) score less than 24
a history of cardiovascular surgery or craniotomy
cardiac failure
respiratory failure

Treatment and study plan

Primary outcomes

decreases in cerebral oxygen saturation (rSO2) during the surgery

Time frame: every 5 minutes throughout the surgery

Secondary outcomes

Change from baseline in Mini-Mental State Exam (MMSE) perioperative period

Time frame: Baseline, 4 day after surgery

Sponsors and collaborators

Lead sponsor

Huazhong University of Science and Technology

Other

Registry information

Official study title

Monitoring Cerebral Oxygen Saturation in Hypertensive Patients Undergoing Major Abdominal Surgery

Acronym: MHPCOS

Important dates

Study start: 2014
Primary completion: 2014
Study completion: 2014
First posted: May 26, 2014
Registry last updated: Nov 11, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed