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Completed

NCT Number: NCT00711165

Mometasone and Markers of Airway Inflammation

A post-marketing study to look at the effects of Asmanex on markers of airway inflammation.

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Key information

Conditions

Asthma Bronchial Diseases Hypersensitivity Hypersensitivity, Immediate Immune System Diseases Lung Diseases Lung Diseases, Obstructive Respiratory Hypersensitivity Respiratory Tract Diseases

Age range

19 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Creighton University Medical Center

Omaha, Nebraska, 68131, United States

About this study

Patients with asthma and not treated with anti-inflammatory medications were studied. This was a parallel, randomized, placebo-controlled study to investigate the effects of Asmanex on markers of airway inflammation including exhaled nitric oxide, airway reactivity, FEV1 and nitrates/nitrites and pH in exhaled breath condensate.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Asthma
  • non-smoker
  • FEV1 of at least 60% predicted

Exclusion criteria

  • Pregnancy or lactation
  • Corticosteroid use in past 30 days

Treatment and study plan

Placebo

Drug

2 puffs, qd

Mometasone furoate

Drug

400 mcg, qd for 8 weeks

Other names: asmanex

Primary outcomes

  1. Exhaled Nitric Oxide

    Time frame: 8 weeks

Secondary outcomes

  1. Airway Reactivity

    Time frame: 8 weeks

Sponsors and collaborators

Lead sponsor

Creighton University

Other

Collaborators

  • Schering-Plough

Registry information

Official study title

The Effects of Mometasone on Markers of Airway Inflammation

Important dates

Study start
2005
Primary completion
2006
Study completion
2006
First posted
Jul 8, 2008
Registry last updated
Jul 8, 2008

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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