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Completed

NCT Number: NCT00364520

Molecular Epidemiology of Benzene-exposed Workers.

The purpose of this study is to investigate the health effects of benzene exposure in workers in Shanghai, China.

Completed

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Key information

Conditions

Hematologic Diseases Hemic and Lymphatic Diseases

Age range

18 year–67 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Joint Sino-US Clinical and Molecular Laboratory (JCML)

Shanghai, 200032, China

About this study

The purpose of this study is to investigate the dose-response relationship between benzene exposure and blood diseases in Shanghai workers and to characterize genetic polymorphisms that are associated with increased risk of developing benzene hematotoxicity.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Worked for at least one year in a monitored environment Have at least one physical examination recorded

-

Exclusion criteria

History of cancer, radiation exposure, chemotherapy

-

Treatment and study plan

Shanghai workers

Other

Primary outcomes

  1. Investigate the dose-response relationship between benzene exposure and blood diseases in Shanghai workers.

    Time frame: August 2003 - December 2009

    Investigate the dose-response relationship between benzene exposure and blood diseases in Shanghai workers

Secondary outcomes

  1. Characterize genetic polymorphisms that are associated with increased risk of developing benzene hematotoxicity.

    Time frame: August 2003 - December 2009

    Characterize genetic polymorphisms that are associated with increased risk of developing benzene hematotoxicity.

Sponsors and collaborators

Lead sponsor

University of Colorado, Denver

Other

Collaborators

  • British Petroleum P.L.C.
  • Chevron Corporation
  • ConocoPhillips
  • Exxon Mobil
  • ExxonMobil Biomedical Sciences, Inc.
  • Fudan University
  • Marathon Ashland
  • Shell Chemicals
  • University of Cincinnati

Registry information

Official study title

Molecular Epidemiology of Benzene-exposed Workers in Shanghai,China

Important dates

Study start
2003
Primary completion
2009
Study completion
2009
First posted
Aug 15, 2006
Registry last updated
May 21, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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