Molecular Assessment of Artemisinin Resistance Markers in Eastern and Western Border Areas of Myanmar

* Artemisinin resistance have been documented in Myanmar and Myanmar artemisinin resistance containment measures have been launched since 2009-2010. * It is important to monitor the spread and magnitude of artemisinin resistant malaria in Myanmar. * So, day-3 surveillance study have been conducted. * Recently artemisinin resistant molecular marker, K13 have been identified and it was used as a tool in this study.

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Key information

Conditions

Day-3 Positive of Parasitaemia Infections Malaria Mosquito-Borne Diseases Parasitic Diseases Prevalence of Drug Resistance Gene Mutation Protozoan Infections Vector Borne Diseases

Age range

2 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Dr. Myat Phone Kyaw

Yangon, 11191, Burma

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

confirmed uncomplicated falciparum malaria patients.
age >2 years
box sex
given informed consent

Exclusion criteria

severe malaria
did not give informed consent
others diseases

Treatment and study plan

Primary outcomes

day-3 parasite positivity

Time frame: 3 days

All of the enrolled patients were monitored with appropriate care up to third day and take the samples on day-3.

Secondary outcomes

Prevalence of the drug resistance marker

Time frame: up to day-3

By using the dried blood spots, drug resistance markers were detected by molecular method.

Sponsors and collaborators

Lead sponsor

Myat Htut Nyunt

Other

Collaborators

Kangwon National University

Registry information

Official study title

Molecular Assessment of Artemisinin Resistance Markers, K13 Kelch Propeller and Multi-drug Resistant Gene Polymorphism in Eastern and Western Border Areas of Myanmar

Important dates

Study start: 2013
Primary completion: 2013
Study completion: 2014
First posted: Jul 23, 2014
Registry last updated: Jul 23, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed