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NCT Number: NCT07455786

Modified Trabeculectomy After Failure of Combined Phaco With GATT

These procedures include deep non-penetrating sclerectomy, viscocanalostomy, and small incision trabeculectomy, avoiding Tenon's capsule.

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Key information

Age range

21 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Assiut univercity

Asyut, 71111, Egypt

Location status: Recruiting

Location contact

hassan lotfy fahmy, prof

CONTACT

[email protected]

01015874517 ext. 002

About this study

Since the advent of GATT or phacogoinotomy as MIGS, ab-externo canaloplasty and NPDS have become essentially obsolete. The ab-interno techniques to vasodilate Schlemm's canal and goniotomy have largely replaced ab-externo canaloplasty.

. Although the GATT procedure and phacogoinotomy is, minimally invasive methods, yet it needs normal functional collector orifice and not respect physiological function of trabecular meshwork,8 as these procedures depend mainly on incision and damage of trabecular meshwork360 degree in GATT 120 in goniotomy, the main disadvantage of these procedures it is not so suitable for narrow angle glaucoma and have many complications as post operative hyphemia with IOP spike, PAS, corneal injury and create cyclodialysis Moreover trabecular meshwork and Schlemm's canal are vital structures can repair themselves through limbal stem cells or even peripheral iris can cover the incision as the part of repair. The main disadvantage is that the trabeculectomy should not be relied upon when the target IOP is in the low teens. Also, these procedures are expensive and need a long learning curve, hyphemia can prevent completion of the operation.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All patients had combined phaco surgery with GATT.
  • All patients had phaco with goinopuncture.

Exclusion criteria

  • Healthy patient.
  • No history of phaco surgery with GATT or goinopuncture.

Treatment and study plan

Modified trabeculectomy

Procedure

deep non-penetrating sclerectomy, viscocanalostomy, and small incision trabeculectomy, avoiding Tenon's capsule

Primary outcomes

  1. IOP

    Time frame: 24 hours

    Intraocular pressure measurement

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Official study title

Modified Trabeculectomy for Management of Early Failure of Combined Phaco With GATT or With Goinopuncture

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Mar 6, 2026
Registry last updated
Mar 6, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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