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OpenTrials
Completed

NCT Number: NCT07166900

Modified Thoracolumbar Interfascial Plane Block Versus Erector Spinae Plane Block For Enhancement Of Quality of Recovery After Lumbar Spine Surgery: A Prospective Randomized Controlled Study.

Aim of study The objective of the current study is to compare the efficacy of ultrasound-guided bilateral modified thoracolumbar interfascial plane (TLIP) block versus erector spinae (ES) block in optimizing early quality of recovery (QOR) following lumbar spine surgery under general anesthesia.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Fayoum university hospital

Al Fayyum, Egypt

About this study

Lumbar spine surgery, a common surgical procedure to alleviate spinal stenosis or disc herniation, is often associated with significant postoperative pain that can hinder early recovery and patient satisfaction. Effective pain management is critical to improve the quality of recovery (QOR), reducing complications, and facilitating early mobilization (1). Regional anesthesia techniques, such as nerve blocks, have gained popularity as part of multimodal analgesia strategies to minimize opioid use and enhance postoperative outcomes. Among these, the thoracolumbar interfascial plane (TLIP) block and the erector spinae (ES) block have emerged as promising ultrasound-guided techniques for managing pain after lumbar spine surgeries (2).

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patient scheduled for elective lumbar spine fixation 2-3 levels.
  • American Society of Anesthesiologists(ASA) class I-III.

Exclusion criteria

  • 1. Obese patients (Body Mass Index> 35). 2. Patients with neurological deficits, cardiopulmonary disease, hepatic or renal impairment.
  • Patients with history of severe allergies to local anesthetics or other medications used during the procedure.
  • Patients with history of coagulation disorder or anticoagulants. 5. Patients with emergency surgeries or re-do surgeries. 6. Patients with systemic infections or infections at the site of injection. 7. Patients with Psychiatric illnesses. 8. Patients with history of drug addiction

Treatment and study plan

Modified Thoracolumbar Interfascial Plane Block

Procedure

The TLIP block, introduced as a modification of the lumbar interfascial plane block, targets the dorsal rami of the thoracolumbar nerves by injecting local anesthetic into the fascial plane between the multifidus and longissimus muscles. This technique is designed to provide analgesia to the posterior elements of the spine, which are often the primary sources of pain after laminectomy

Primary outcomes

  1. Quality of Recovery (QOR)

    Time frame: 24 hours postoperatively

    Assessed using the QOR-15 questionnaire at 24 hours postoperatively

Sponsors and collaborators

Lead sponsor

Fayoum University

Other

Registry information

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Sep 11, 2025
Registry last updated
May 13, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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