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Completed

NCT Number: NCT07289373

Moderate Versus High-intensity Interval Training in Children With Diplegia.

The aim is to compare the effects of moderate-intensity training and high-intensity interval training on gait, energy expenditure, and functional mobility in children with spastic diplegia. Methods: Thirty children with spastic diplegic cerebral palsy were allocated randomly into two groups (n=15 each). The group A and the group B. Assessment of functional mobility and energy expenditure and gait analysis for all children of both groups were assessed before and after the suggested period of treatment.

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Key information

Age range

3 year–5 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of Physical Therapy, Cairo University

Giza, Egypt

About this study

Methods: Thirty children with with spastic diplegic cerebral palsy were allocated randomly into two groups ( n= 15 each). The group A (received aerobic training with moderate intensity endurance training "MIET" by walking or running on a treadmill) and the group B (received aerobic training exercises in a form of high intensity interval training "HIT" by walking or running on a treadmill). Treatment was delivered for 20minutes, 3 times per week for two successive months. Assessment of functional mobility and energy expenditure using Timed Up and Go(TUG) test and Energy Expenditure Index Heart Rate(EEIHR) respectively, while gait analysis for both lower limb angles of (hips and Knees) assessment using 2d gait analysis by( Kinovea) software. All children of both groups assessed before and after the suggested period of treatment.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Their age ranged from 3 to 5 years old
  • The degree of spasticity ranged from 1+ to 2 according to modified Ashworth scale
  • They were able to walk with limitations or holding on according to Gross Motor Function Classification System (II, III).
  • They were able to follow instructions and understand commands.
  • They were medically stable.

Exclusion criteria

  • Children who had bone and tendon lengthening surgeries within the last 6 months.
  • Children with lung and heart diseases and disorders.
  • Children with fixed deformities in joints and bones of lower limbs.
  • Children performing different sorts of physical activities.
  • Children receiving any medications affecting muscle and mental function or antiepileptic drugs that affect the mental function.
  • Children with perceptual defects.
  • Children with any visual or sound-related issues.

Treatment and study plan

Moderate intensity training

Procedure

Moderate-intensity endurance training (MIET) by walking or running on a treadmill

High Intensity Interval Training

Procedure

Aerobic training exercises in a form of high-intensity interval training (HIIT) by walking or running on a treadmill

Primary outcomes

  1. Gait

    Time frame: 2 months

    Assessed by 2D gait analysis

  2. Functional mobility

    Time frame: 2 months

    Assessed by Time Up and Go test

  3. Energy Expenditure

    Time frame: 2 months

    Assessed by Energy Expenditure Index Heart Rate

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Moderate Intensity Training Versus High Intensity Interval Training on Gait and Energy Expenditure in Children With Spastic Diplegia.

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Dec 17, 2025
Registry last updated
Dec 17, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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