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Active, Not Recruiting

NCT Number: NCT05375344

Mobility and Voiding Exercises in Older Women With Urinary Incontinence (MoVEonUp)

A prospective, two-arm randomized clinical trial utilizing a multidimensional intervention to reduce falls in older women with Urinary Urge Incontinence. The intervention consist of general balance and strength training, bladder training and urge suppression, and home hazard assessments. The control group will receive informational booklets on fall prevention and behavioral treatment for urinary urge incontinence.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Age range

70 year and older

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Female
  • 70 or older
  • Living independently in the community
  • Willingness to be randomized.
  • Ability to read and understand English
  • Be able to provide informed consent
  • Low physical activity (physically active for 30 minutes or more less than or equal to 2 days per week on average over the past 6 months) per PAS
  • Ambulatory (defined as patient not confined to bed or wheelchair OR ability to walk with or without an assistive device)
  • Self-reported moderate to severe urge-predominant UI based on the ICIQ-SF > 6 (Q 1+2+3)
  • Not planning to initiate new UI or overactive bladder (OAB) treatment during the study duration
  • Capable of participation in an exercise program without exacerbating any pre-existing condition(s), as determined by the study PI or designee

Exclusion criteria

  • Pelvic organ prolapse passed the hymen (per patient report)
  • Undergoing active treatment for cancer (other than non-melanoma skin cancer)
  • Uncorrected visual or hearing loss.
  • Other urinary conditions or procedures that may affect continence status for example: urethral diverticulum, previous augmentation cystoplasty
  • Progressive neurodegenerative disease e.g. Parkinson's disease, multiple sclerosis per patient report
  • History of stroke or carotid sensitivity (i.e. syncopal falls) per patient report
  • Unstable cardiac disease per patient report
  • Fracture or joint replacement within the last six months per patient report
  • Significant cognitive impairment (defined as a modified TICs score of < 27)
  • Per PI discretion, participant cannot enroll in study

Treatment and study plan

Exercise group

Behavioral

Home-based exercise group intervention

Primary outcomes

  1. Change in number of falls between the baseline visit and 1 year

    Time frame: 12 months

    number of falls reported in a falls diary

Secondary outcomes

  1. Change in urinary incontinence score on the International Consultation on Incontinence Questionnaire Short Form (ICIQ-SF) between baseline visit and 1 year

    Time frame: 12 months

    Change in International Consultation on Incontinence Questionnaire Short Form (ICIQ-SF). A minimum score is 0, a maximum score is 21 with a higher score indicating higher severity.

Sponsors and collaborators

Lead sponsor

University of Pennsylvania

Other

Registry information

Official study title

MoVE on Up: Mobility and Voiding Exercises in Older Women With Urinary Incontinence

Acronym: MOVEONUP

Important dates

Study start
2022
Primary completion
2026
Study completion
2026
First posted
May 16, 2022
Registry last updated
Feb 5, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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