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OpenTrials
Completed

NCT Number: NCT03390010

Misoprostol Versus Active Management of Labour in CS

Several treatment strategies are emplemented to prevent post delivery hemorage and decreasing maternal morbidity and mortality .

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Key information

Conditions

Cesarean Section

Age range

18 year–42 year

Sex eligibility

Female

Study type

Interventional

Phase

Phase 1

Primary location

Algazeerah

Giza, Egypt

About this study

Many approved drugs are used in prophylaxis against postpartum hemorage from these medications are the (syntocinon combined with methergine ) that are known as active management of labour drugs .

Moreover there is misotac , that also guards against postpartum hemorage .

All these medications act in a different way to cause uterine contraction post delivery to prevent uterine atony .

-Here we are comparing the additive value of misotac intrauterine to syntocinon and methergine in comparison to the usually used syntocinon plus methergine .

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • • All patients included in this research were aged 18-42 years, pregnant 37 weeks till 42 weeks
  • no medical disorders with pregnancy e.g DM, HTN. All patients were subjected to full history taking, examination.

Exclusion criteria

  • Exclusion Criteria:
  • The following patients were excluded , GA before 37 weeks or after 42 weeks , medical disorders with pregnancy eg. DM with pregnancy, HTN with pregnancy

Treatment and study plan

Misoprostol + syntocinon and using extra uterotonic drugs when needed ; methergine

Drug

medical prophylaxis against postpartum atony and postpartum hemorage by giving misoprostol plus syntocinon and using extra uterotonic drugs when needed ; methergine, carboprost

Other names: DrugsMisoprostol plus syntocinon and using extra uterotonic drugs when needed ; methergine , carboprost

Syntocinon and using extra uterotonic drugs when needed ; methergine carboprost

Drug

medical prophylaxis against postpartum atony and postpartum hemorage by giving syntocinon and using extra uterotonic drugs when needed ; methergine, carboprost

Other names: drugs ( syntocinon and using extra uterotonic drugs when needed ; methergine, carboprost

Primary outcomes

  1. The number of participants who passed cesarean section without postpartum hemorage

    Time frame: within 2 days post CS

Sponsors and collaborators

Lead sponsor

Aljazeera Hospital

Other

Collaborators

  • Cairo University

Registry information

Official study title

Intrauterine Misoprostol With Active Management of Labour Versus Active Management of Labour for Prevebtion of Postpartum Hemorage in Cesarean Section ,Randomized Controlled Trial

Important dates

Study start
2017
Primary completion
2018
Study completion
2018
First posted
Jan 4, 2018
Registry last updated
Nov 16, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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