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NCT Number: NCT07380958

Mirror Therapy as an Adjunct to Rehabilitation Following Total Knee Arthroplasty

The investigators are looking to see if using a mirror during knee exercises after a knee replacement helps participants with less pain and/or better knee range of motion.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

Purpose: To examine the effectiveness of mirror therapy combined with standard care physical therapy on knee range of motion (ROM), pain levels, and physical function in individuals following a total knee arthroplasty (TKA).

Background: Following a TKA, patients often present with numerous impairments including joint stiffness, pain, decreased strength, and impaired mobility. These limitations can inhibit functional progress during rehabilitation and recovery. Mirror therapy is a potential treatment option that may assist in reducing these impairments and improving recovery following TKA.

Study Activities: Active and sham group activities will add-on to the physical therapy session and are considered part of standard care, with no change to the current billing process. Both groups will participate in ROM activities, consistent with standard PT care, as part of a billable treatment. The active group with do standard practice ROM activities while looking at a mirror and the sham group will perform ROM activities without a mirror.

Interventions:

  • Treatment will start within 2 weeks (14 days) of the total knee replacement.
  • There will be 8 sessions within a 4-week time frame.

Data Analysis: Demographic information will be reported using descriptive statistics. Analyses will use linear mixed-effects models with fixed effects for Group, Time, and the Group × Time interaction, and with subject-level random effects to account for repeated measures. The primary inference will be the Group × Time interaction.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Candidates that have been screened and deemed eligible for a TKA and received a TKA 14 days or less post operation.
  • English speaking
  • Able to understand and follow instructions
  • Has at least 5 degrees of knee extension to 100 degrees of knee flexion AROM on the contralateral knee
  • Able to perform unilateral stance on contralateral side for at least 5 seconds (balance assistance allowed)
  • Able to perform exercises

Exclusion criteria

  • Post-surgical complications (DVT, infection, nerve injury, vascular injury)
  • Pain rating on NPRS no more than a 4/10 on the contralateral LE
  • Significant scar or deformity of the contralateral LE
  • Visual impairments causing an inability to see the reflection in a mirror

Treatment and study plan

Mirror Therapy

Other

Using a mirror while participating in ROM activities.

Sham intervention

Other

Using a covered mirror, unable to see reflection. subject will perform all ROM activities

Primary outcomes

  1. Pain NRS (Pain Numerical Rating Scale)

    Time frame: Every visit, visits 1, 2, 3, 4, 5, 6, 7 & 8. Visits start within 14 days of the TKA and occur a total of 8 times within a 4 weeks time frame.

    Subject rates pain from 0-10 with 0 being no pain and 10 being the worst pain

  2. Knee Flexion and Extension Goniometry

    Time frame: Every visit, visits 1, 2, 3, 4, 5, 6, 7 & 8. Visits start within 14 days of the TKA and occur a total of 8 times within a 4 weeks time frame.

    A measurement of knee flexion and knee extension, using a goniometer, will be completed.

Secondary outcomes

  1. Gait Speed

    Time frame: Visit 1 and visit 8. Visits start within 14 days of the TKA and occur a total of 8 times within a 4 weeks time frame.

    Subject's gait speed will be measured in meters/second.

  2. Knee Injury and Osteoarthritis Outcome Score, Junior (KOOS Jr)

    Time frame: Visit 1 and visit 8. Visits start within 14 days of the TKA and occur a total of 8 times within a 4 weeks time frame.

    Knee Injury and Osteoarthritis Outcome Score, Junior (KOOS Jr) is a short, 7-question survey used by doctors to quickly assess a patient's knee pain, stiffness, and daily function. The raw score is converted to a 0-100 scale with a score of 0 = total disability and 100 = full function without pain.

Study contacts

Contact information is provided by the study sponsor or research team.

Marissa Hanlon, PT, DPT, GCS, CSCS

CONTACT

[email protected]

315-464-6892

Sponsors and collaborators

Lead sponsor

State University of New York - Upstate Medical University

Other

Registry information

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Feb 2, 2026
Registry last updated
Feb 2, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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