Mineral-Homeostasis in Continuous Renal Replacement Therapy

Acute renal failure is a common complication in intensive care unit patients. In 10% of cases renal replacement therapy becomes necessary. Current devices have increase filter patency and efficacy. However, magnesium, calcium and phosphate are eliminated as well. However, the extend of this elimination hase not been quantified. Thus, we want to

1. record retrospectively how often abnormal values for phosphate, magnesium and calcium occurred during routine renal replacement therapy in 2011 and 2012. 2. prospectively evaluate the same parameters during routine treatment in 2013 and 2014

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Key information

Conditions

Acute Renal Failure Acute Kidney Injury Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Kidney Diseases Male Urogenital Diseases Renal Insufficiency Urogenital Diseases Urologic Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Interdisziplinäre Intensivstation Universitätsklinikum Düsseldorf

Düsseldorf, 40225, Germany

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

intensive care unit patients with acute renal failure undergoing continuous renal replacement therapy
older than 18 years of age

Exclusion criteria

age less than 18 years
pregnancy
contraindications against continuous renal replacement therapy

Treatment and study plan

Primary outcomes

Incidence of hypo-phosphate,-magnesium and calcaemia

Time frame: approximately 28 days

Participants will be followed for the duration of ICU stay, an expected average of 28 days

Sponsors and collaborators

Lead sponsor

Heinrich-Heine University, Duesseldorf

Other

Registry information

Official study title

Phosphate, Magnesium and Calcium-Homeostasis in Patients With Acute Renal Failure and Continuous Renal Replacement Therapy

Important dates

Study start: 2013
Primary completion: 2015
Study completion: 2015
First posted: Sep 19, 2013
Registry last updated: Aug 20, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed