Skip to main content
OpenTrials
Completed

NCT Number: NCT01144689

Mindfulness Training for Smoking Cessation

The purpose of this study is to assess the effects of mindfulness training (MT) compared to standard Smoking Cessation Therapy (SCT) on smoking cessation and stress provocation in individuals trying to quit smoking.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Cigarette Smoking Behavior Chemically-Induced Disorders Health Behavior Mental Disorders Nicotine Dependence Smoking Smoking Cessation Substance-Related Disorders Tobacco Smoking Tobacco Use Tobacco Use Disorder

Age range

18 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

VA Connecticut Healthcare System

West Haven, Connecticut, 06516, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Between the ages of 18 and 60
  • Smoking 10 or more cigarettes per day
  • Fewer than 3 months of smoking abstinence in the past year
  • Motivated to stop smoking

Exclusion criteria

  • Current use of psychoactive medications that have not been at a stable dose for the past six months, are used as mood stabilizers, or are used as smoking cessation treatments. Individuals who are on psychoactive medications that are stable, not mood stabilizers, and not used for smoking cessations are excluded from fMRI sessions but not smoking cessation treatment.
  • Use of another investigational drug within 30 days
  • Any serious or unstable disease within 6 months
  • Meets criteria for substance dependence within the past year
  • Left handed (will be excluded from fMRI only)

Treatment and study plan

Mindfulness Training

Behavioral

8 sessions of behavioral treatment for smoking cessation

Smoking cessation therapy

Behavioral

8 sessions of behavioral treatment for smoking cessation

Primary outcomes

  1. Between group differences in continuous abstinence

    Time frame: during treatment and 6, 12 and 18 weeks after treatment initiation

Secondary outcomes

  1. Between group differences in perceived stress

    Time frame: 6, 12 and 18 weeks after treatment initiation

Sponsors and collaborators

Lead sponsor

Yale University

Other

Registry information

Official study title

Assessing Mindfulness Training as a Mechanistic Probe for Stress-Induced Brain Activation and Relapse Prevention for Tobacco Addiction

Important dates

Study start
2009
Primary completion
2013
Study completion
2013
First posted
Jun 15, 2010
Registry last updated
Jul 7, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.