Li Huili Hospital, Ningbo Medical Center
Ningbo, Zhejiang, 315046, China
Completed
NCT Number: NCT06261372
Mindfulness Meditation Combined With Progressive Muscle Relaxation Training for Uremic Sarcopenia
To study the effect of mindfulness meditation combined with progressive muscle relaxation training on clinical efficacy and quality of life in maintenance hemodialysis (MHD) patients with sarcopenia. Eligible sarcopenic patients in our hospital were randomly assigned to a control group (n = 24) and an intervention group (n = 25). The control group received conventional dialysis treatment, while the intervention group received mindfulness meditation combined with progressive muscle relaxation training during the interdialysis period in addition to conventional dialysis treatment. The effect of the intervention was evaluated after 12 weeks.To observe whether the combined intervention training can improve the motor ability and quality of life of patients with sarcopenia in a short period of time.
Completed
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Notify MeKey information
Conditions
Age range
18 year–80 year
Sex eligibility
All sexes
Study type
Interventional
Phase
Not applicable
Primary location
Who can participate
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- Patients who met the sarcopenia criteria established by the Asian Working Group for Sarcopenia (AWGS) in 2014
- Stable condition and generally good health status
- Good compliance and ability to collaborate well with the physician
- Undergoing hemodialysis three times per week for at least three months, with a KT/V ≥ 1.2
- No significant cardiovascular or cerebrovascular complications (such as severe heart failure, severe arrhythmias, angina, and cerebrovascular diseases)
- Patients with sarcopenia who met the clinical diagnostic criteria were selected to ensure the quality of the included patients
Exclusion criteria
- Inability to complete handgrip strength, 6-meter walk test, 10 sit-to-stand tests, and the use of bioelectrical impedance analysis (BIA) due to contraindications
- Coexistence of mental illness or severe cognitive or communication disorders
Treatment and study plan
The mindfulness meditation combined with progressive muscle relaxation training .
BehavioralThe first part is progressive muscle relaxation training. The second part is mindfulness meditation training.
Primary outcomes
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10 sit-to-stand test in seconds
Time frame: 3 months
The 10 sit-stand test represents exercise ability, and the shorter the time, the greater the exercise ability.
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Grip strength in kilograms
Time frame: 3 months
Grip strength represents exercise ability, and the larger it is, the more exercise ability it is.Its minimum value is zero, and its maximum value is unlimited.
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6-meter walk test in metre per second
Time frame: 3 months
6-meter walk test represents exercise ability, and the larger it is, the more exercise ability it is.Its minimum value is zero metre per second, and its maximum value is unlimited.
-
KDQOLTM(Kidney Disease Quality of Life short Form) score
Time frame: 3 months
The KDQOLTM score is between 0 and 100, and the higher the score, the better the health
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interleukin-6 (IL-6)
Time frame: 3 months
Interleukin 6 represents an inflammatory marker, and its concentration is 20pg/ml or less.
-
high-sensitivity C-reactive protein (hsCRP)
Time frame: 3 months
hsCRP represents an inflammatory marker, and its concentration ranges from 0.0 to 10mg/L.
-
albumin(ALB)
Time frame: 3 months
Albumin represents a nutritional indicator, and its concentration ranges from 40 to 55g/L.
-
prealbumin (PA）
Time frame: 3 months
Prealbumin represents a nutritional indicator, and its concentration ranges from 0.20 to 0.43g/l.
Sponsors and collaborators
Lead sponsor
Ningbo Medical Center Lihuili Hospital
Other Gov
Registry information
Official study title
The Influence of Mindfulness Meditation Combined With Progressive Muscle Relaxation Training on the Clinical Efficacy and Quality of Life of Hemodialysis Patients With Sarcopenia
Important dates
- Study start
- 2023
- Primary completion
- 2023
- Study completion
- 2023
- First posted
- Feb 15, 2024
- Registry last updated
- Feb 15, 2024
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.