Mindfulness and Meditation-Based Relapse Prevention for Substance Use Disorders

Mindfulness and meditation based relapse prevention has been proposed as an adjunctive approach for individuals with substance use disorders (SUDs). This completed pilot observational case series describes outcomes from three de-identified participants who completed an eight-week mindfulness and meditation program designed to reduce stress, enhance coping skills, and support sustained recovery.

Participants demonstrated improvements in perceived stress and mindfulness following the intervention. Two participants experienced relapse within 10-12 months, while one participant maintained long-term sobriety. This small case series provides descriptive clinical insights and supports the feasibility of mindfulness-based interventions in real-world treatment settings.

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Key information

Conditions

Substance Use Disorders Addiction Disorders Addiction Psychological Behavioral Health Chemically-Induced Disorders Meditation Mental Disorders Mindfulness Based Stress Reduction Prevention Substance-Related Disorders

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Bout Me Healing

Boca Raton, Florida, 33496, United States

About this study

This pilot observational case series evaluated an eight-week mindfulness and meditation-based relapse prevention program delivered to three de-identified adults with substance use disorders. The intervention included weekly guided mindfulness sessions, daily home practice, and group discussions focused on awareness of cravings, emotional regulation, and relapse prevention strategies.

Outcomes were assessed using self-reported perceived stress and mindfulness measures, along with qualitative clinical interviews and participant journals to monitor relapse behavior. All participants demonstrated improvements in perceived stress and mindfulness. Relapse occurred in two participants within one year, while one participant maintained long-term sobriety.

This study was exploratory and descriptive in nature, with a small sample size. Ethics review was not required as all participants were de-identified and the study was conducted as a clinical case series. Findings are intended to inform future research and larger-scale studies of mindfulness-based relapse prevention interventions.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Adults aged 18 years or older
History of substance use disorder (any substance)
Enrolled in or referred to an eight-week mindfulness and meditation-based relapse prevention program
Willing and able to participate in weekly guided sessions, daily home practice, and group discussions
Able to provide self-reported information on stress, mindfulness, and relapse experiences

Exclusion criteria

Individuals under 18 years of age
Inability or unwillingness to participate in mindfulness or meditation exercises
Severe cognitive impairment or psychiatric condition preventing participation in group or home practice
Participation in concurrent structured relapse prevention programs outside of this study

Treatment and study plan

Mindfulness and Meditation-Based Relapse Prevention Program

Behavioral

The mindfulness and meditation-based relapse prevention program consisted of an eight-week structured intervention delivered as part of routine clinical practice. Participants engaged in weekly guided mindfulness meditation sessions, daily individual home practice, and facilitated group discussions. The intervention focused on developing awareness of thoughts, emotions, cravings, and stress responses, with an emphasis on nonjudgmental observation and emotional regulation. Sessions included mindfulness exercises, breathing techniques, body awareness practices, and reflective discussion related to relapse prevention and coping strategies. The program was not designed as a randomized or controlled intervention and was implemented uniformly across participants.

Primary outcomes

Change in Perceived Stress and Mindfulness Following Mindfulness-Based Relapse Prevention Program

Time frame: Baseline (pre-intervention) to end of the eight-week program

The primary outcome is the change in perceived stress and mindfulness levels in participants completing an eight-week mindfulness and meditation-based relapse prevention program. Stress was assessed using the Perceived Stress Scale and mindfulness using the Five Facet Mindfulness Questionnaire. Observations were collected through participant journals and clinical interviews, comparing baseline to post-intervention outcomes. This outcome reflects the feasibility and potential impact of mindfulness-based practices in supporting emotional regulation and coping strategies for individuals with substance use disorders.

Sponsors and collaborators

Lead sponsor

Bout Me Healing

Industry

Registry information

Official study title

Observational Case Series of Mindfulness- and Meditation-Based Relapse Prevention for Substance Use Disorders (MBRP-SUD)

Acronym: MBRP-SUD

Important dates

Study start: 2015
Primary completion: 2015
Study completion: 2016
First posted: Feb 18, 2026
Registry last updated: Feb 18, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed