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NCT Number: NCT07745023

Mind-Body Interventions for the Improvement of Quality of Life, Stress, and Sleep Quality Among Survivors of Breast, Prostate, Endometrial, or Colorectal Cancer

This clinical trial studies how well mind-body interventions work in improving quality of life (QOL), stress, and sleep quality among survivors of breast, prostate, endometrial, or colorectal cancer. For many cancer survivors, the experience of cancer extends well beyond the completion of therapy. Common long-term effects include fatigue, cognitive impairment, anxiety, depression, sleep disturbance, and diminished physical function, all of which contribute to reduced QOL and overall health. Yoga, a mind-body intervention, utilizes breathwork, meditation, and gentle movement to help reduce activity in the body's nervous system. Breathwork and meditation have been shown to improve heart rate variability (a measure of the body's ability to adapt to stress). Movement-based practices may offer added benefit by supporting coordination and physical resiliency, aspects that are often reduced after cancer treatment and can lead to decreased QOL. This trial may help researchers determine whether a mind-body intervention that includes breathwork and meditation, as well as an intervention that includes breathwork and meditation plus gentle movement can work to improve QOL, stress, and sleep quality among survivors of breast, prostate, endometrial, or colorectal cancer.

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Key information

Conditions

Breast Cancer Stage I Breast Diseases Breast Neoplasms Colonic Diseases Colorectal Cancer Colorectal Neoplasms Digestive System Diseases Digestive System Neoplasms Gastrointestinal Diseases Gastrointestinal Neoplasms Intestinal Diseases Intestinal Neoplasms Neoplasms Neoplasms by Site Rectal Diseases Skin Diseases Skin and Connective Tissue Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

PRIMARY OBJECTIVE:

I. Pilot test video and/or audio content consisting of six, 15-minute breathwork and meditation videos/audio, and six, 15-minute guided, gentle movement videos developed for this intervention for feasibility and acceptability, and provide preliminary data on QOL in cancer (breast, colon, endometrial, and prostate) survivors using patient-reported outcomes measurements completed at pre- and post- intervention.

SECONDARY OBJECTIVES:

I. Evaluate program satisfaction using structured questionnaires for all participants at post-intervention.

II. Identify perceived barriers, evaluate facilitators, and identify recommendations for future scaling and delivery in varied survivorship settings

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Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Received a diagnosis of invasive, non-metastatic breast, colorectal, endometrial, or prostate cancer within the past 12 months
  • Have completed active anti-cancer therapy (hormonal, bisphosphonate, or androgen therapy is allowed)
  • Able to safely participate in light-weight physical activity (e.g. gentle yoga)

Exclusion criteria

  • Individuals with skeletal instabilities, cardio-pulmonary comorbidities, or other conditions that may preclude safe participation in light physical activity
  • Pregnant or nursing female participants
  • Unwilling or unable to follow protocol requirements
  • Any condition that, in the Investigator's opinion, deems the participant an unsuitable candidate
  • Unable to complete survey questionnaires in English

Treatment and study plan

Media Intervention

Other

View breathwork and meditation videos

Mind-body intervention

Procedure

Complete breathwork exercises

Meditation Therapy

Procedure

Complete Meditation exercises

Primary outcomes

  1. Change in quality of life

    Time frame: Baseline up to 6 weeks

    Patients view guided breathwork, meditation, and gentle yoga movement videos and complete these exercises over 30 minutes weekly for 6 weeks on study. Patients also wear an activity tracker throughout the study

Secondary outcomes

  1. Adherence Rate

    Time frame: UP to 6 weeks

    Proportion of participants who complete at least 80% of the assigned interventions

Study contacts

Contact information is provided by the study sponsor or research team.

Kathryn G Glaser

CONTACT

[email protected]

716*845-2300

Sponsors and collaborators

Lead sponsor

Roswell Park Cancer Institute

Other

Registry information

Official study title

Influence of Mind-Body Interventions on Cancer-Related Symptom Management in Survivors

Important dates

Study start
2026
Primary completion
2028
Study completion
2029
First posted
Aug 4, 2026
Registry last updated
Aug 4, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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