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OpenTrials
Completed

NCT Number: NCT01572961

Microvascular Function Assessment in Healthy Subjects

Current stimulation induces microvascular dilation in human skin. The investigators aimed to study (1) whether the current vasodilation is amplified after two segmental current stimulation as compared to one stimulation; (2) whether this amplification relies on prostaglandin-sensitive mechanisms. A double-blind randomized placebo-controlled crossover trial is conducted in Angers, France.

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Key information

Conditions

Physiology of Microvascular Skin

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University Hospital

Angers, Maine et Loire, 49933, France

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age > or equal to 18 years old
  • Healthy subjects

Exclusion criteria

  • Aspirin allergy

Treatment and study plan

acetylsalicilic acids (Aspirin)

Drug

single oral dose of 1g.

Other names: Aspegic 1000mg, sanofi aventis.

Placebo

Drug

Primary outcomes

  1. The increase of Laser Doppler Blood Flow after the second current stimulation

    Time frame: 1 hour

Secondary outcomes

  1. The increase of Laser Doppler Blood Flow after the second current stimulation after aspirin administration

    Time frame: 1 hour

Sponsors and collaborators

Lead sponsor

University Hospital, Angers

Other Gov

Registry information

Official study title

Amélioration Des Techniques d'étude de la Micro-cirulation cutanée Chez Des Sujets Sains

Acronym: MICROTEC

Important dates

Study start
2010
Primary completion
2012
Study completion
2013
First posted
Apr 6, 2012
Registry last updated
Feb 12, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.