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Recruiting

NCT Number: NCT07054008

Microsurgery and Periodontal Healing

Scientists do research to answer important questions which might help change or improve the way we do things in the future.

The investigators know that using glasses with special attachments that provide magnification (dental loupes) for dental procedures results in better healing than not using magnification. This study will test if using a microscope, that gives much higher magnification, can result in even better healing than using dental loupes.

Recruiting

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Key information

Age range

18 year–18 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Texas Health Science Center at San Antonio

San Antonio, Texas, 78229, United States

Location status: Recruiting

Location contact

Angela A Palaiologou-Gallis, DDS., MS.

CONTACT

[email protected]

210-567-3567

About this study

A two-arm split mouth randomized controlled trial investigating the effect of using an experimental microsurgical approach with a digital microscope (Group 1) or standard of care surgical approach with dental loupes (Group 2) on post-operative wound healing of two standardized vertical releasing incisions. The split mouth design will ensure that each patient serves as their own control.

The hypothesis is that the wound closure technique in Group 1: Microsurgical approach with digital microscope will have improved periodontal flap vertical releasing incision wound healing as compared to the Group 2: Standard of Care surgical approach with dental loupes.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Ability of subject to understand and the willingness to sign a written informed consent document.
  • Males and females; Age 18 -89 years old
  • Require surgical flap treatment of periodontal disease
  • Either maxillary or mandibular arch
  • ASA I or II
  • Has consistent transportation for all clinical and study visits

Exclusion criteria

  • Pregnancy, or those planning to become pregnant
  • Diabetics with an HbA1c >7.1
  • Not eligible for surgical periodontal therapy
  • Require vertical or horizontal hard tissue augmentation
  • Non-English speaking

Treatment and study plan

Microsurgical approach with Digital Microscope

Procedure

The incision will be sutured with the use of a digital microscope (30 X) (Group 1). The microsurgical approach is a research only procedure that may add time to the total surgical time (< 6%).

Other names: Microsurgery

Primary outcomes

  1. Early wound healing index

    Time frame: One, two and three weeks

    Assessment of early soft tissue wound healing

Secondary outcomes

  1. Difference in time between procedures

    Time frame: End of surgical procedure at last suture placement

    The time needed for suturing the incision with the digital microscope (Group 1) and with standard of care dental loupes (Group 2) will be documented immediately after placement of the last suture.

Study contacts

Contact information is provided by the study sponsor or research team.

Angela Palaiologou-Gallis, DDS

CONTACT

[email protected]

210-450-3715

Sponsors and collaborators

Lead sponsor

The University of Texas Health Science Center at San Antonio

Other

Registry information

Official study title

The Effect of Microsurgical Approach to Periodontal Flap Healing: A Randomized Controlled Trial

Important dates

Study start
2025
Primary completion
2027
Study completion
2027
First posted
Jul 8, 2025
Registry last updated
Nov 12, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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