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Completed

NCT Number: NCT01687452

Microparticles, Vector of Genetic Information During HIV Infection

The aim of the investigators study is to demonstrate in healthy subjects and a cohort of patients infected with HIV, the presence of miRNAs in circulating peripheral blood microparticles (MPs).

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Key information

Conditions

HIV,

Age range

30 year–50 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Assistance Publique Hopitaux de Marseille

Marseille, 13354, France

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age of 40 +/-10 years
  • Seronegativity for the HIV 2
  • Patients of the group A: seropositivity for the HIV 1 confirmed in ELISA and Western Blot for at least 2 years and having never received from antiretroviral treatment, with a viral plasmatique load > 1000 copies / ml
  • Patients of the group B: seropositivity for the HIV 1 confirmed in ELISA and Western Blot for at least 2 years and under stable antiretroviral treatment for at least 6 months, with a viral load undetectable plasmatique (< 40 copies / ml)
  • patients of the group C : Matching on the age (+/-3 years) to a patient
  • Be considered healthy by the Investigator after a clinical examination Seronegativity for the HIV 1 confirmed in ELISA the day of the taking

Exclusion criteria

group A et B

  • Age of < 30 years and > in 50 years
  • Seropositivity for the HIV 2

group C Seropositivity for the HIV 2

  • Be under medicinal treatment

Treatment and study plan

blood samples

Biological

Primary outcomes

  1. NUMBER OF miRNAs

    Time frame: 2 YEARS

Secondary outcomes

  1. Demonstrate the presence of miRNAs in microparticles

    Time frame: 2 YEARS

Sponsors and collaborators

Lead sponsor

Assistance Publique Hopitaux De Marseille

Other

Registry information

Official study title

Microparticles, Vector of Genetic Information During HIV Infection ?

Important dates

Study start
2011
Primary completion
2012
Study completion
2012
First posted
Sep 19, 2012
Registry last updated
Sep 1, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.