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Active, Not Recruiting

NCT Number: NCT07305558

Microdochectomy for Chronic Non Dilated Single Duct Nipple Discharge

The goal of this clinical trial is to evaluate the efficacy of a new technique in treatment of single milk duct discharge. The main questions it aims to answer are:

Does ultrasound guided microdochectomy is feasible in non dilated milk duct? What are the surgical outcomes of this technique?

Participants will:

Had ultrasound microdochectomy After discharge, patients will visit the clinic twice every week for two weeks, a visit or call after 3 month

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Nipple Discharge Breast Diseases Female Urogenital Diseases and Pregnancy Complications Galactorrhea Lactation Disorders Pregnancy Complications Puerperal Disorders Skin Diseases Skin and Connective Tissue Diseases Urogenital Diseases

Age range

18 year and older

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

faculty of medicine, Zagazig University

Zagazig, 44519, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • females above 18 years old with single not dilated milk duct discharge after failure of medical treatment

Exclusion criteria

  • breast cancer
  • patients with multiple or dilated milk duct discharge.
  • contraindications to surgery or ‬anaesthesia
  • patient above 18 years old
  • patients refuse to participate in the study

Treatment and study plan

ultrasound guided microdochectomy

Procedure

ultrasound was used to perform microdochectomy for single not dilated milk duct without cannulation

Primary outcomes

  1. Nipple discharge

    Time frame: from first day after surgery to 3 months after surgery

    stop of spontaneous and induced nipple discharge by absence of stain on dressing and clothes and by squeezing the nipple

Secondary outcomes

  1. operation time

    Time frame: from skin incision to closure

    operation time is calculated in minutes

  2. Bleeding

    Time frame: from skin incision to skin closure

    Bleeding is evaluated in mm using gravimetric and direct vision methods

  3. post operative pain

    Time frame: from the day of surgery to one week after surgery

    post operative pain is assessed using the visual analogue scale. The total score is out of 10 (1 means painless, 10 means painful)

  4. hospital stay

    Time frame: from the first day of surgery to 3 days after surgery

    hospital stay is recorded in days

  5. wound infection

    Time frame: from one day to 2 weeks after surgery

    wound infection diagnosed by direct vision of pus or ultrasound of the breast

Sponsors and collaborators

Lead sponsor

Zagazig University

Other Gov

Registry information

Official study title

Ultrasound Guided Microdochectomy in Chronic Non Dilated Single Duct Nipple Discharge

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Dec 26, 2025
Registry last updated
Dec 26, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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