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Completed

NCT Number: NCT01944566

Microbial Community Transplantation on the Armpit.

The malodour generation of a person's armpit is caused by the bacteria thriving on that armpit. In order to alter or reduce once bad body odour, the living microbial community on the armpit of a non-malodorous person will be transmitted (or up scaled and transmitted) to the armpit of a malodorous person. The odour is evaluated by a trained smelling panel, the bacteria living on the armpit is examined by means of molecular techniques. The microbial transplantation and its follow-up happens under the supervision of a medical doctor.

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Key information

Conditions

Heavy, Bad Odour From Armpit

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Ghent University, Ghent, Belgium

Loading trial locations.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • bad armpit odour

Treatment and study plan

Microbial transplant

Biological

Every subject has 2 armpits; 1 armpit is treated, the other one is not treated. There is a microbial transplant from armpit bacteria.

Primary outcomes

  1. Reduction of bad odour of the armpit.

    Time frame: 24 evaluations in approximately 10 weeks.

    Odour evaluation by a trained smelling panel. The measurements take place before (once), during the treatment week (5 times) and after the treatment (2x per week during 2 months).

  2. Molecular characterisation of the bacterial community after microbial transplantation.

    Time frame: 24 evaluations in approximately 10 weeks.

    Microbial evaluation by means of DNA extraction and Denaturing Gradient Gel Electrophoresis. The measurements take place before (once), during the treatment week (5 times) and after the treatment (2x per week during 2 months).

Secondary outcomes

  1. Reduction of bad odour of the armpit over a longer period.

    Time frame: after 4 months

    Odour evaluation by a trained smelling panel.

  2. Reduction of bad odour of the armpit over a longer period.

    Time frame: after 6 months

    Odour evaluation by a trained smelling panel.

  3. Molecular characterisation of the bacterial community after microbial transplantation.

    Time frame: after 4 months

    Microbial evaluation by means of DNA extraction and Denaturing Gradient Gel Electrophoresis.

  4. Molecular characterisation of the bacterial community after microbial transplantation.

    Time frame: After 6 months

    Microbial evaluation by means of DNA extraction and Denaturing Gradient Gel Electrophoresis.

Sponsors and collaborators

Lead sponsor

University Ghent

Other

Collaborators

  • University Hospital, Ghent

Registry information

Official study title

Microbial Community Transplantation on the Armpit in Order to Reduce the Malodour Generation on Armpit.

Important dates

Study start
2013
Primary completion
2015
Study completion
2015
First posted
Sep 17, 2013
Registry last updated
Dec 2, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.