Microarray Analysis of microRNA Expression Profiles in Cutaneous Squamous Cell Carcinoma

MicroRNAs (miRNAs) are a novel class of short RNAs which have shown to be dysregulated in a variety of cancers. Data of miRNA expression in cutaneous squamous cell carcinoma (cSCC) is very limited and microarray based genome wide miRNA expression profiles of cSCC have not been investigated so far.

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Key information

Conditions

Cutaneous Squamous Cell Carcinoma

Age range

1 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Department of Dermatology, Venereology and Allergology, Dermatologic Surgery Unit, Ruhr-University Bochum

Bochum, North Rhine-Westphalia, 44791, Germany

About this study

Patients with cutaneous SCC were enrolled in the present study. Tumor biopsies were taken from the center of the tumor. Adjacent healthy skin was biopsied as a control (intraindividual control). miRNA expression profiles of specimen were detected by microarray miRNA expression profiling. Microarray results were confirmed by TaqMan real-time quantitative polymerase chain reaction (RT-PCR).

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

cutaneous squamous cell carcinoma

Exclusion criteria

other skin cancer than cutaneous squamous cell carcinoma

Sponsors and collaborators

Lead sponsor

Ruhr University of Bochum

Other

Registry information

Important dates

Study start: 2011
Primary completion: 2011
Study completion: 2011
First posted: Dec 29, 2011
Registry last updated: Oct 16, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed