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NCT Number: NCT06312332

Michigan Emergency Department Improvement Collaborative (MEDIC) Alert; Pulmonary Embolism (PE)

This study is a quality improvement project to evaluate health care management of pulmonary embolism (PE) patients. The researchers are testing an intervention to determine if it prevents unnecessary hospital admissions.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Conditions

Pulmonary Embolism Cardiovascular Diseases Disease Attributes Embolism Embolism and Thrombosis Emergencies Lung Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms Respiratory Tract Diseases Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Michigan Emergency Department Improvement Collaborative partners

Ann Arbor, Michigan, 48109, United States

About this study

The study team anticipates that there will be 5800 acute PE patients over multiple sites. The study team is not recruiting additional sites into the study but tracking of acute PE patients continues.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Participation in MEDIC collaborative
  • Identified site physician champion
  • Annual volume of acute PE ≥80 (measured in 2022)

Exclusion criteria

  • Pediatric-only hospital/ED
  • No site physician champion identified
  • Annual volume of acute PE <80 (measured in 2022)
  • Existing formal clinical pathway for outpatient management of low-risk PE

Treatment and study plan

Pulmonary Embolism (PE) Care in Emergency Department (ED)

Behavioral

Utilize implementation mapping to facilitate intervention development and evaluation that can be disseminated broadly in diverse settings. Intervention to include a structured education program for clinicians on home management of patients with low-risk PE led by regional/national leaders, the development of Clinician pre-commitment, point-of-care nudge including a clinical guideline integrated into an electronic health record clinical decision support, facilitated medication access, and dedicated outpatient rapid-follow up.

Primary outcomes

  1. Change in proportion of patients discharged home from Emergency Department (ED)

    Time frame: 3 months Pre-intervention, Up to 18 months Post-intervention

    Reported by participating center indicating the proportion of patients discharged home from ED

Sponsors and collaborators

Lead sponsor

University of Michigan

Other

Collaborators

  • National Heart, Lung, and Blood Institute (NHLBI)

Registry information

Official study title

Michigan Emergency Department Improvement Collaborative (MEDIC) AltERnaTives to Admission for Pulmonary Embolism

Important dates

Study start
2024
Primary completion
2026
Study completion
2026
First posted
Mar 15, 2024
Registry last updated
Jun 1, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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